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Antimicrobial peptide LL-37 ameliorates a murine sepsis model via the induction of microvesicle release from neutrophils

Sepsis is a life-threatening disease caused by systemic dys-regulated inflammatory response to infection. We previously revealed that LL-37, a human cathelicidin antimicrobial peptide, improves the survival of cecal ligation and puncture septic mice. Ectosomes, microvesicles released from neutrophil...

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Detalles Bibliográficos
Autores principales: Kumagai, Yumi, Murakami, Taisuke, Kuwahara-Arai, Iba, Toshiaki, Reich, Johannes, Nagaoka, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556193/
https://www.ncbi.nlm.nih.gov/pubmed/32600088
http://dx.doi.org/10.1177/1753425920936754