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Antimicrobial peptide LL-37 ameliorates a murine sepsis model via the induction of microvesicle release from neutrophils
Sepsis is a life-threatening disease caused by systemic dys-regulated inflammatory response to infection. We previously revealed that LL-37, a human cathelicidin antimicrobial peptide, improves the survival of cecal ligation and puncture septic mice. Ectosomes, microvesicles released from neutrophil...
Autores principales: | Kumagai, Yumi, Murakami, Taisuke, Kuwahara-Arai, Iba, Toshiaki, Reich, Johannes, Nagaoka, Isao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556193/ https://www.ncbi.nlm.nih.gov/pubmed/32600088 http://dx.doi.org/10.1177/1753425920936754 |
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