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Net protein balance correlates with expression of autophagy, mitochondrial biogenesis, and fat metabolism‐related genes in skeletal muscle from older adults

The mechanisms leading to sarcopenia, the main cause for frailty in older adults, are still unclear. Autophagy and the ubiquitin‐proteasome system (UPS) may play a role in mediating muscle protein breakdown related to sarcopenia. In addition to loss of muscle mass, compromised muscle performance obs...

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Detalles Bibliográficos
Autores principales: Wu, Hexirui, Jang, Jiwoong, Dridi, Sami, Ferrando, Arny A., Wolfe, Robert R., Kim, Il‐Young, Baum, Jamie I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556313/
https://www.ncbi.nlm.nih.gov/pubmed/33063954
http://dx.doi.org/10.14814/phy2.14575