Cargando…

Activation-induced cytidine deaminase localizes to G-quadruplex motifs at mutation hotspots in lymphoma

Diffuse large B-cell lymphoma (DLBCL) is a molecularly heterogeneous group of malignancies with frequent genetic abnormalities. G-quadruplex (G4) DNA structures may facilitate this genomic instability through association with activation-induced cytidine deaminase (AID), an antibody diversification e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Ying-Zhi, Jenjaroenpun, Piroon, Wongsurawat, Thidathip, Byrum, Stephanie D, Shponka, Volodymyr, Tannahill, David, Chavez, Elizabeth A, Hung, Stacy S, Steidl, Christian, Balasubramanian, Shankar, Rimsza, Lisa M, Kendrick, Samantha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Cancer Gene Regulation, Chromatin, and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556405/ https://www.ncbi.nlm.nih.gov/pubmed/33094287 http://dx.doi.org/10.1093/narcan/zcaa029

Ejemplares similares

FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA
por: Sarkies, Peter, et al.
Publicado: (2012)

Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression
por: Fernando, Himesh, et al.
Publicado: (2009)

Guanine quadruplex structures localize to heterochromatin
por: Hoffmann, Roland F., et al.
Publicado: (2016)

Detection of G-quadruplex DNA in mammalian cells
por: Henderson, Alexander, et al.
Publicado: (2014)

Activation-induced deaminase is critical for the establishment of DNA methylation patterns prior to the germinal center reaction
por: Català-Moll, Francesc, et al.
Publicado: (2021)

CNBP controls transcription by unfolding DNA G-quadruplex structures
por: David, Aldana P, et al.
Publicado: (2019)

G-quadruplex ligands mediate downregulation of DUX4 expression
por: Ciszewski, Lukasz, et al.
Publicado: (2020)

Vimentin binds to G-quadruplex repeats found at telomeres and gene promoters
por: Ceschi, Silvia, et al.
Publicado: (2022)

TERRA regulates DNA G-quadruplex formation and ATRX recruitment to chromatin
por: Tsai, Ru-Xuan, et al.
Publicado: (2022)

G-quadruplexes as novel cis-elements controlling transcription during embryonic development
por: David, Aldana P., et al.
Publicado: (2016)

Heterochromatin protein 1α interacts with parallel RNA and DNA G-quadruplexes
por: Roach, Ruby J, et al.
Publicado: (2020)

Identification of LARK as a novel and conserved G-quadruplex binding protein in invertebrates and vertebrates
por: Niu, Kangkang, et al.
Publicado: (2019)

Novel roles of an intragenic G-quadruplex in controlling microRNA expression and cardiac function
por: Zhu, Min, et al.
Publicado: (2021)

Telomeric i-motifs and C-strands inhibit parallel G-quadruplex extension by telomerase
por: El-Khoury, Roberto, et al.
Publicado: (2023)

p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells
por: Periyasamy, Manikandan, et al.
Publicado: (2017)

Unexpected diversity in eukaryotic transcription revealed by the retrotransposon hotspot family of Trypanosoma brucei
por: Florini, Francesca, et al.
Publicado: (2019)

Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevance
por: Zizza, Pasquale, et al.
Publicado: (2016)

G-quadruplex DNA contributes to RNA polymerase II-mediated 3D chromatin architecture
por: Yuan, Jun, et al.
Publicado: (2023)

Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential
por: Johnson, Jay E., et al.
Publicado: (2010)

Evidence of the formation of G-quadruplex structures in the promoter region of the human vascular endothelial growth factor gene
por: Sun, Daekyu, et al.
Publicado: (2011)

Location dependence of the transcriptional response of a potential G-quadruplex in gene promoters under oxidative stress
por: Fleming, Aaron M, et al.
Publicado: (2019)

The MDM2 inducible promoter folds into four-tetrad antiparallel G-quadruplexes targetable to fight malignant liposarcoma
por: Lago, Sara, et al.
Publicado: (2021)

HRAS is silenced by two neighboring G-quadruplexes and activated by MAZ, a zinc-finger transcription factor with DNA unfolding property
por: Cogoi, Susanna, et al.
Publicado: (2014)

MyoD- and FoxO3-mediated hotspot interaction orchestrates super-enhancer activity during myogenic differentiation
por: Peng, Xianlu L., et al.
Publicado: (2017)

Double-stranded flanking ends affect the folding kinetics and conformational equilibrium of G-quadruplexes forming sequences within the promoter of KIT oncogene
por: Vesco, Guglielmo, et al.
Publicado: (2021)

Yin Yang 1 contains G-quadruplex structures in its promoter and 5′-UTR and its expression is modulated by G4 resolvase 1
por: Huang, Weiwei, et al.
Publicado: (2012)

A cis-element with mixed G-quadruplex structure of NPGPx promoter is essential for nucleolin-mediated transactivation on non-targeting siRNA stress
por: Wei, Pei-Chi, et al.
Publicado: (2013)

Telomeric repeat-containing RNA/G-quadruplex-forming sequences cause genome-wide alteration of gene expression in human cancer cells in vivo
por: Hirashima, Kyotaro, et al.
Publicado: (2015)

Genome-wide profiles of H2AX and γ-H2AX differentiate endogenous and exogenous DNA damage hotspots in human cells
por: Seo, Jungmin, et al.
Publicado: (2012)

The human AP-endonuclease 1 (APE1) is a DNA G-quadruplex structure binding protein and regulates KRAS expression in pancreatic ductal adenocarcinoma cells
por: Pramanik, Suravi, et al.
Publicado: (2022)

G-quadruplexes mark alternative lengthening of telomeres
por: Yang, Sunny Y, et al.
Publicado: (2021)

The DNA dioxygenase Tet1 regulates H3K27 modification and embryonic stem cell biology independent of its catalytic activity
por: Chrysanthou, Stephanie, et al.
Publicado: (2022)

Acetylated Histone H3K9 is associated with meiotic recombination hotspots, and plays a role in recombination redundantly with other factors including the H3K4 methylase Set1 in fission yeast
por: Yamada, Shintaro, et al.
Publicado: (2013)

A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing
por: Fan, Huitao, et al.
Publicado: (2021)

A non-canonical DNA structure is a binding motif for the transcription factor SP1 in vitro
por: Raiber, Eun-Ang, et al.
Publicado: (2012)

Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer
por: Xu, Chenxi, et al.
Publicado: (2021)

CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins
por: Chen, Mengqian, et al.
Publicado: (2023)

Toward predictive R-loop computational biology: genome-scale prediction of R-loops reveals their association with complex promoter structures, G-quadruplexes and transcriptionally active enhancers
por: Kuznetsov, Vladimir A, et al.
Publicado: (2018)

Toward predictive R-loop computational biology: genome-scale prediction of R-loops reveals their association with complex promoter structures, G-quadruplexes and transcriptionally active enhancers
por: Kuznetsov, Vladimir A, et al.
Publicado: (2018)

The transcription factor Sox5 modulates Sox10 function during melanocyte development
por: Stolt, C. Claus, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_egdo9dh9sr2d4tok7qbltsu59a