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Activation-induced cytidine deaminase localizes to G-quadruplex motifs at mutation hotspots in lymphoma
Diffuse large B-cell lymphoma (DLBCL) is a molecularly heterogeneous group of malignancies with frequent genetic abnormalities. G-quadruplex (G4) DNA structures may facilitate this genomic instability through association with activation-induced cytidine deaminase (AID), an antibody diversification e...
Autores principales: | Xu, Ying-Zhi, Jenjaroenpun, Piroon, Wongsurawat, Thidathip, Byrum, Stephanie D, Shponka, Volodymyr, Tannahill, David, Chavez, Elizabeth A, Hung, Stacy S, Steidl, Christian, Balasubramanian, Shankar, Rimsza, Lisa M, Kendrick, Samantha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556405/ https://www.ncbi.nlm.nih.gov/pubmed/33094287 http://dx.doi.org/10.1093/narcan/zcaa029 |
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