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Optical characteristics after Descemet membrane endothelial keratoplasty: 1-year results
PURPOSE: To evaluate the corneal characteristics after Descemet membrane endothelial keratoplasty (DMEK) compared with normal corneas. METHODS: Patients who underwent DMEK at Yokohama Minami Kyosai Hospital were included and prospectively evaluated pre-operatively and at postoperative months 1, 3, 6...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556451/ https://www.ncbi.nlm.nih.gov/pubmed/33052928 http://dx.doi.org/10.1371/journal.pone.0240458 |
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author | Hayashi, Takahiko Kobayashi, Akira Takahashi, Hidenori Oyakawa, Itaru Kato, Naoko Yamaguchi, Takefumi |
author_facet | Hayashi, Takahiko Kobayashi, Akira Takahashi, Hidenori Oyakawa, Itaru Kato, Naoko Yamaguchi, Takefumi |
author_sort | Hayashi, Takahiko |
collection | PubMed |
description | PURPOSE: To evaluate the corneal characteristics after Descemet membrane endothelial keratoplasty (DMEK) compared with normal corneas. METHODS: Patients who underwent DMEK at Yokohama Minami Kyosai Hospital were included and prospectively evaluated pre-operatively and at postoperative months 1, 3, 6, and 12, and compared to healthy controls. Corneal characteristics evaluated included corneal curvature (keratometric value [KV]; D), central corneal thickness (CCT), peripheral corneal thickness (PCT), and corneal higher-order aberrations [HOAs] at 6.0 mm diameter, calculated by anterior segment optical coherence tomography and logarithm of the minimal angle of resolution [logMAR]. RESULTS: A total of 30 eyes of 30 patients (6 men, 24 women, mean age 73.4 ± 7.4 years) were included and compared with 31 age-matched healthy control eyes (13 men, 18 women; mean age 73.0 ± 6.7 years). LogMAR after DMEK improved from 0.87 ± 0.07 preoperatively to 0.04 ± 0.07 at 12 months postoperatively (p<0.001). Although anterior KVs of DMEK eyes were similar to those of control eyes, posterior KVs were significantly larger (-6.4 ± 0.3 D vs. -6.3 ± 0.2 D; p = 0.02). Total HOAs after DMEK improved from 1.94 ± 1.05 μm preoperatively to 1.05 ± 0.16 μm at 12 months postoperatively (p<0.001), which was significantly higher than that in control eyes (0.63 ± 0.06) (p<0.001). Despite the similar CCTs in the two groups, the PCT was significantly larger in DMEK eyes (704 ± 41 μm vs 669 ± 38 μm, p = 0.002) at 12 months. CONCLUSION: Despite achieving good visual function and excellent corneal clarity, eyes that underwent DMEK showed a steeper posterior KV and higher corneal HOAs than normal eyes even at 12 months after surgery. |
format | Online Article Text |
id | pubmed-7556451 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-75564512020-10-21 Optical characteristics after Descemet membrane endothelial keratoplasty: 1-year results Hayashi, Takahiko Kobayashi, Akira Takahashi, Hidenori Oyakawa, Itaru Kato, Naoko Yamaguchi, Takefumi PLoS One Research Article PURPOSE: To evaluate the corneal characteristics after Descemet membrane endothelial keratoplasty (DMEK) compared with normal corneas. METHODS: Patients who underwent DMEK at Yokohama Minami Kyosai Hospital were included and prospectively evaluated pre-operatively and at postoperative months 1, 3, 6, and 12, and compared to healthy controls. Corneal characteristics evaluated included corneal curvature (keratometric value [KV]; D), central corneal thickness (CCT), peripheral corneal thickness (PCT), and corneal higher-order aberrations [HOAs] at 6.0 mm diameter, calculated by anterior segment optical coherence tomography and logarithm of the minimal angle of resolution [logMAR]. RESULTS: A total of 30 eyes of 30 patients (6 men, 24 women, mean age 73.4 ± 7.4 years) were included and compared with 31 age-matched healthy control eyes (13 men, 18 women; mean age 73.0 ± 6.7 years). LogMAR after DMEK improved from 0.87 ± 0.07 preoperatively to 0.04 ± 0.07 at 12 months postoperatively (p<0.001). Although anterior KVs of DMEK eyes were similar to those of control eyes, posterior KVs were significantly larger (-6.4 ± 0.3 D vs. -6.3 ± 0.2 D; p = 0.02). Total HOAs after DMEK improved from 1.94 ± 1.05 μm preoperatively to 1.05 ± 0.16 μm at 12 months postoperatively (p<0.001), which was significantly higher than that in control eyes (0.63 ± 0.06) (p<0.001). Despite the similar CCTs in the two groups, the PCT was significantly larger in DMEK eyes (704 ± 41 μm vs 669 ± 38 μm, p = 0.002) at 12 months. CONCLUSION: Despite achieving good visual function and excellent corneal clarity, eyes that underwent DMEK showed a steeper posterior KV and higher corneal HOAs than normal eyes even at 12 months after surgery. Public Library of Science 2020-10-14 /pmc/articles/PMC7556451/ /pubmed/33052928 http://dx.doi.org/10.1371/journal.pone.0240458 Text en © 2020 Hayashi et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Hayashi, Takahiko Kobayashi, Akira Takahashi, Hidenori Oyakawa, Itaru Kato, Naoko Yamaguchi, Takefumi Optical characteristics after Descemet membrane endothelial keratoplasty: 1-year results |
title | Optical characteristics after Descemet membrane endothelial keratoplasty: 1-year results |
title_full | Optical characteristics after Descemet membrane endothelial keratoplasty: 1-year results |
title_fullStr | Optical characteristics after Descemet membrane endothelial keratoplasty: 1-year results |
title_full_unstemmed | Optical characteristics after Descemet membrane endothelial keratoplasty: 1-year results |
title_short | Optical characteristics after Descemet membrane endothelial keratoplasty: 1-year results |
title_sort | optical characteristics after descemet membrane endothelial keratoplasty: 1-year results |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556451/ https://www.ncbi.nlm.nih.gov/pubmed/33052928 http://dx.doi.org/10.1371/journal.pone.0240458 |
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