The O-GlcNAc transferase OGT is a conserved and essential regulator of the cellular and organismal response to hypertonic stress

The conserved O-GlcNAc transferase OGT O-GlcNAcylates serine and threonine residues of intracellular proteins to regulate their function. OGT is required for viability in mammalian cells, but its specific roles in cellular physiology are poorly understood. Here we describe a conserved requirement fo...

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Detalles Bibliográficos
Autores principales: Urso, Sarel J., Comly, Marcella, Hanover, John A., Lamitina, Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556452/
https://www.ncbi.nlm.nih.gov/pubmed/33006972
http://dx.doi.org/10.1371/journal.pgen.1008821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556452/
https://www.ncbi.nlm.nih.gov/pubmed/33006972
http://dx.doi.org/10.1371/journal.pgen.1008821

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