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A materials-science perspective on tackling COVID-19

The ongoing SARS-CoV-2 pandemic highlights the importance of materials science in providing tools and technologies for antiviral research and treatment development. In this Review, we discuss previous efforts in materials science in developing imaging systems and microfluidic devices for the in-dept...

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Autores principales: Tang, Zhongmin, Kong, Na, Zhang, Xingcai, Liu, Yuan, Hu, Ping, Mou, Shan, Liljeström, Peter, Shi, Jianlin, Tan, Weihong, Kim, Jong Seung, Cao, Yihai, Langer, Robert, Leong, Kam W., Farokhzad, Omid C., Tao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556605/
https://www.ncbi.nlm.nih.gov/pubmed/33078077
http://dx.doi.org/10.1038/s41578-020-00247-y
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author Tang, Zhongmin
Kong, Na
Zhang, Xingcai
Liu, Yuan
Hu, Ping
Mou, Shan
Liljeström, Peter
Shi, Jianlin
Tan, Weihong
Kim, Jong Seung
Cao, Yihai
Langer, Robert
Leong, Kam W.
Farokhzad, Omid C.
Tao, Wei
author_facet Tang, Zhongmin
Kong, Na
Zhang, Xingcai
Liu, Yuan
Hu, Ping
Mou, Shan
Liljeström, Peter
Shi, Jianlin
Tan, Weihong
Kim, Jong Seung
Cao, Yihai
Langer, Robert
Leong, Kam W.
Farokhzad, Omid C.
Tao, Wei
author_sort Tang, Zhongmin
collection PubMed
description The ongoing SARS-CoV-2 pandemic highlights the importance of materials science in providing tools and technologies for antiviral research and treatment development. In this Review, we discuss previous efforts in materials science in developing imaging systems and microfluidic devices for the in-depth and real-time investigation of viral structures and transmission, as well as material platforms for the detection of viruses and the delivery of antiviral drugs and vaccines. We highlight the contribution of materials science to the manufacturing of personal protective equipment and to the design of simple, accurate and low-cost virus-detection devices. We then investigate future possibilities of materials science in antiviral research and treatment development, examining the role of materials in antiviral-drug design, including the importance of synthetic material platforms for organoids and organs-on-a-chip, in drug delivery and vaccination, and for the production of medical equipment. Materials-science-based technologies not only contribute to the ongoing SARS-CoV-2 research efforts but can also provide platforms and tools for the understanding, protection, detection and treatment of future viral diseases.
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spelling pubmed-75566052020-10-15 A materials-science perspective on tackling COVID-19 Tang, Zhongmin Kong, Na Zhang, Xingcai Liu, Yuan Hu, Ping Mou, Shan Liljeström, Peter Shi, Jianlin Tan, Weihong Kim, Jong Seung Cao, Yihai Langer, Robert Leong, Kam W. Farokhzad, Omid C. Tao, Wei Nat Rev Mater Review Article The ongoing SARS-CoV-2 pandemic highlights the importance of materials science in providing tools and technologies for antiviral research and treatment development. In this Review, we discuss previous efforts in materials science in developing imaging systems and microfluidic devices for the in-depth and real-time investigation of viral structures and transmission, as well as material platforms for the detection of viruses and the delivery of antiviral drugs and vaccines. We highlight the contribution of materials science to the manufacturing of personal protective equipment and to the design of simple, accurate and low-cost virus-detection devices. We then investigate future possibilities of materials science in antiviral research and treatment development, examining the role of materials in antiviral-drug design, including the importance of synthetic material platforms for organoids and organs-on-a-chip, in drug delivery and vaccination, and for the production of medical equipment. Materials-science-based technologies not only contribute to the ongoing SARS-CoV-2 research efforts but can also provide platforms and tools for the understanding, protection, detection and treatment of future viral diseases. Nature Publishing Group UK 2020-10-14 2020 /pmc/articles/PMC7556605/ /pubmed/33078077 http://dx.doi.org/10.1038/s41578-020-00247-y Text en © Springer Nature Limited 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review Article
Tang, Zhongmin
Kong, Na
Zhang, Xingcai
Liu, Yuan
Hu, Ping
Mou, Shan
Liljeström, Peter
Shi, Jianlin
Tan, Weihong
Kim, Jong Seung
Cao, Yihai
Langer, Robert
Leong, Kam W.
Farokhzad, Omid C.
Tao, Wei
A materials-science perspective on tackling COVID-19
title A materials-science perspective on tackling COVID-19
title_full A materials-science perspective on tackling COVID-19
title_fullStr A materials-science perspective on tackling COVID-19
title_full_unstemmed A materials-science perspective on tackling COVID-19
title_short A materials-science perspective on tackling COVID-19
title_sort materials-science perspective on tackling covid-19
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556605/
https://www.ncbi.nlm.nih.gov/pubmed/33078077
http://dx.doi.org/10.1038/s41578-020-00247-y
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