Expression of the immune modulator secretory leukocyte protease inhibitor (SLPI) in colorectal cancer liver metastases and matched primary tumors is associated with a poorer prognosis

Secretory leukocyte protease inhibitor (SLPI), a pleiotropic protein expressed by healthy intestinal epithelial cells, functions as an inhibitor of NF-κB and neutrophil proteases and exerts antimicrobial activity. We previously showed SLPI suppresses intestinal epithelial chemokine production in res...

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Detalles Bibliográficos
Autores principales: Nugteren, Sandrine, Goos, Jeroen A.C.M., Delis-van Diemen, Pien M., Simons-Oosterhuis, Ytje, Lindenbergh-Kortleve, Dicky J., van Haaften, Daniëlle H., Sanders, Joyce, Meijer, Gerrit A., Fijneman, Remond J.A., Samsom, Janneke N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556627/
https://www.ncbi.nlm.nih.gov/pubmed/33101778
http://dx.doi.org/10.1080/2162402X.2020.1832761

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