ATR addiction in multiple myeloma: synthetic lethal approaches exploiting established therapies

Therapeutic strategies designed to interfere with cancer cell DNA damage response have led to the widespread use of PARP inhibitors for BRCA1/2-mutated cancers. In the haematological cancer multiple myeloma, we sought to identify analogous synthetic lethality mechanisms that could be exploited in es...

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Detalles Bibliográficos
Autores principales: Botrugno, Oronza A., Bianchessi, Silvia, Zambroni, Desirée, Frenquelli, Michela, Belloni, Daniela, Bongiovanni, Lucia, Girlanda, Stefania, Di Terlizzi, Simona, Ferrarini, Marina, Ferrero, Elisabetta, Ponzoni, Maurilio, Marcatti, Magda, Tonon, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556682/
https://www.ncbi.nlm.nih.gov/pubmed/33054085
http://dx.doi.org/10.3324/haematol.2018.215210

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