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Predictive value of initial CT scan for various adverse outcomes in patients with COVID-19 pneumonia

BACKGROUND: Chest computed tomography (CT) scan is frequently used in the diagnosis of COVID-19 pneumonia. OBJECTIVES: This study investigates the predictive value of CT severity score (CSS) for length-of-stay (LOS) in hospital, initial disease severity, ICU admission, intubation, and mortality. MET...

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Autores principales: Khosravi, Bardia, Aghaghazvini, Leila, Sorouri, Majid, Naybandi Atashi, Sara, Abdollahi, Mohammad, Mojtabavi, Helia, Khodabakhshi, Marjan, Motamedi, Fatemeh, Azizi, Fatemeh, Rajabi, Zeynab, Kasaeian, Amir, Sima, Ali Reza, Davarpanah, Amir H., Radmard, Amir Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556824/
https://www.ncbi.nlm.nih.gov/pubmed/33097297
http://dx.doi.org/10.1016/j.hrtlng.2020.10.005
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author Khosravi, Bardia
Aghaghazvini, Leila
Sorouri, Majid
Naybandi Atashi, Sara
Abdollahi, Mohammad
Mojtabavi, Helia
Khodabakhshi, Marjan
Motamedi, Fatemeh
Azizi, Fatemeh
Rajabi, Zeynab
Kasaeian, Amir
Sima, Ali Reza
Davarpanah, Amir H.
Radmard, Amir Reza
author_facet Khosravi, Bardia
Aghaghazvini, Leila
Sorouri, Majid
Naybandi Atashi, Sara
Abdollahi, Mohammad
Mojtabavi, Helia
Khodabakhshi, Marjan
Motamedi, Fatemeh
Azizi, Fatemeh
Rajabi, Zeynab
Kasaeian, Amir
Sima, Ali Reza
Davarpanah, Amir H.
Radmard, Amir Reza
author_sort Khosravi, Bardia
collection PubMed
description BACKGROUND: Chest computed tomography (CT) scan is frequently used in the diagnosis of COVID-19 pneumonia. OBJECTIVES: This study investigates the predictive value of CT severity score (CSS) for length-of-stay (LOS) in hospital, initial disease severity, ICU admission, intubation, and mortality. METHODS: In this retrospective study, initial CT scans of consecutively admitted patients with COVID-19 pneumonia were reviewed in a tertiary hospital. The association of CSS with the severity of disease upon admission and the final adverse outcomes was assessed using Pearson's correlation test and logistic regression, respectively. RESULTS: Total of 121 patients (60±16 years), including 54 women and 67 men, with positive RT-PCR tests were enrolled. We found a significant but weak correlation between CSS and qSOFA, as a measure of disease severity (r: 0.261, p = 0.003). No significant association was demonstrated between CSS and LOS. Patients with CSS>8 had at least three-fold higher risk of ICU admission, intubation, and mortality. CONCLUSIONS: CSS in baseline CT scan of patients with COVID-19 pneumonia can predict adverse outcomes and is weakly correlated with initial disease severity.
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spelling pubmed-75568242020-10-15 Predictive value of initial CT scan for various adverse outcomes in patients with COVID-19 pneumonia Khosravi, Bardia Aghaghazvini, Leila Sorouri, Majid Naybandi Atashi, Sara Abdollahi, Mohammad Mojtabavi, Helia Khodabakhshi, Marjan Motamedi, Fatemeh Azizi, Fatemeh Rajabi, Zeynab Kasaeian, Amir Sima, Ali Reza Davarpanah, Amir H. Radmard, Amir Reza Heart Lung Article BACKGROUND: Chest computed tomography (CT) scan is frequently used in the diagnosis of COVID-19 pneumonia. OBJECTIVES: This study investigates the predictive value of CT severity score (CSS) for length-of-stay (LOS) in hospital, initial disease severity, ICU admission, intubation, and mortality. METHODS: In this retrospective study, initial CT scans of consecutively admitted patients with COVID-19 pneumonia were reviewed in a tertiary hospital. The association of CSS with the severity of disease upon admission and the final adverse outcomes was assessed using Pearson's correlation test and logistic regression, respectively. RESULTS: Total of 121 patients (60±16 years), including 54 women and 67 men, with positive RT-PCR tests were enrolled. We found a significant but weak correlation between CSS and qSOFA, as a measure of disease severity (r: 0.261, p = 0.003). No significant association was demonstrated between CSS and LOS. Patients with CSS>8 had at least three-fold higher risk of ICU admission, intubation, and mortality. CONCLUSIONS: CSS in baseline CT scan of patients with COVID-19 pneumonia can predict adverse outcomes and is weakly correlated with initial disease severity. Elsevier Inc. 2021 2020-10-14 /pmc/articles/PMC7556824/ /pubmed/33097297 http://dx.doi.org/10.1016/j.hrtlng.2020.10.005 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Khosravi, Bardia
Aghaghazvini, Leila
Sorouri, Majid
Naybandi Atashi, Sara
Abdollahi, Mohammad
Mojtabavi, Helia
Khodabakhshi, Marjan
Motamedi, Fatemeh
Azizi, Fatemeh
Rajabi, Zeynab
Kasaeian, Amir
Sima, Ali Reza
Davarpanah, Amir H.
Radmard, Amir Reza
Predictive value of initial CT scan for various adverse outcomes in patients with COVID-19 pneumonia
title Predictive value of initial CT scan for various adverse outcomes in patients with COVID-19 pneumonia
title_full Predictive value of initial CT scan for various adverse outcomes in patients with COVID-19 pneumonia
title_fullStr Predictive value of initial CT scan for various adverse outcomes in patients with COVID-19 pneumonia
title_full_unstemmed Predictive value of initial CT scan for various adverse outcomes in patients with COVID-19 pneumonia
title_short Predictive value of initial CT scan for various adverse outcomes in patients with COVID-19 pneumonia
title_sort predictive value of initial ct scan for various adverse outcomes in patients with covid-19 pneumonia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556824/
https://www.ncbi.nlm.nih.gov/pubmed/33097297
http://dx.doi.org/10.1016/j.hrtlng.2020.10.005
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