Increased MLKL mRNA level in the PBMCs is correlated with autoantibody production, renal involvement, and SLE disease activity

BACKGROUND: Necroptosis is a form of regulated necrosis that is involved in various autoimmune diseases. Mixed lineage kinase domain-like pseudokinase (MLKL) has been identified as a key executor of necroptosis; however, the significance of MLKL in peripheral blood mononuclear cells (PBMCs) of syste...

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Detalles Bibliográficos
Autores principales: Zhang, Mingjiao, Jie, Hongyu, Wu, Yong, Han, Xinai, Li, Xing, He, Yi, Shi, Xingliang, Luo, Yuwei, Sun, Ying, Yang, Jinlong, Yang, Jing, Quan, Shulv, Lao, Xiaobin, Tan, Liping, Sun, Erwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557011/
https://www.ncbi.nlm.nih.gov/pubmed/33054864
http://dx.doi.org/10.1186/s13075-020-02332-7

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