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Population genetic and biophysical evidences reveal that purifying selection shapes the genetic landscape of Plasmodium falciparum RH ligands in Chhattisgarh and West Bengal, India

BACKGROUND: Reticulocyte binding protein-like homologs (RHs) are currently being evaluated as anti-erythrocytic stage vaccine targets against Plasmodium falciparum malaria. Present study explores the possible evolutionary drivers shaping the genetic organization of Pfrhs in Indian parasite populatio...

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Detalles Bibliográficos
Autores principales:	Ghoshal, Sharmistha, Chowdhury, Pramita, Ray, Sanhita, Mitra, Mitashree, Kanjilal, Sumana Datta, Sen, Srikanta, Dasgupta, Anjan Kr., Sengupta, Sanghamitra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557104/ https://www.ncbi.nlm.nih.gov/pubmed/33054833 http://dx.doi.org/10.1186/s12936-020-03433-z

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