Endothelial, pericyte and tumor cell expression in glioblastoma identifies fibroblast activation protein (FAP) as an excellent target for immunotherapy

OBJECTIVES: Targeted immunotherapies such as chimeric antigen receptor (CAR)‐T cells are emerging as attractive treatment options for glioblastoma, but rely on identification of a suitable tumor antigen. We validated a new target antigen for glioblastoma, fibroblast activation protein (FAP), by unde...

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Detalles Bibliográficos
Autores principales: Ebert, Lisa M, Yu, Wenbo, Gargett, Tessa, Toubia, John, Kollis, Paris M, Tea, Melinda N, Ebert, Brenton W, Bardy, Cedric, van den Hurk, Mark, Bonder, Claudine S, Manavis, Jim, Ensbey, Kathleen S, Oksdath Mansilla, Mariana, Scheer, Kaitlin G, Perrin, Sally L, Ormsby, Rebecca J, Poonnoose, Santosh, Koszyca, Barbara, Pitson, Stuart M, Day, Bryan W, Gomez, Guillermo A, Brown, Michael P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557106/
https://www.ncbi.nlm.nih.gov/pubmed/33082953
http://dx.doi.org/10.1002/cti2.1191

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