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Hereditary hemochromatosis promotes colitis and colon cancer and causes bacterial dysbiosis in mice
Hereditary hemochromatosis (HH), an iron-overload disease, is a prevalent genetic disorder. As excess iron causes a multitude of metabolic disturbances, we postulated that iron overload in HH disrupts colonic homeostasis and colon–microbiome interaction and exacerbates the development and progressio...
Autores principales: | Sivaprakasam, Sathish, Ristic, Bojana, Mudaliar, Nithya, Hamood, Abdul N., Colmer-Hamood, Jane, Wachtel, Mitchell S., Nevels, Anna G., Kottapalli, Kameswara R., Ganapathy, Vadivel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557149/ https://www.ncbi.nlm.nih.gov/pubmed/32955078 http://dx.doi.org/10.1042/BCJ20200392 |
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