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Nicardipine Loaded Solid Phospholipid Extrudates for the Prevention of Cerebral Vasospasms: In Vitro Characterization

The aim of the study was to develop nicardipine loaded phospholipid extrudates as an alternative for PLA/PLGA-based implants for the prevention of cerebral vasospasms. Extrudates of different mixtures of saturated and unsaturated phosphatidylcholine (PC) were produced and characterized by DSC, micro...

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Detalles Bibliográficos
Autores principales: Zlomke, Christin, Albrecht, Johannes, Mäder, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557531/
https://www.ncbi.nlm.nih.gov/pubmed/32872184
http://dx.doi.org/10.3390/pharmaceutics12090817