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Covalent inhibitors: a rational approach to drug discovery

Covalent inhibitors are recognized as an important component in drug discovery and therapeutics. Since the first appearance of covalent inhibitors in the late 18th century, the field has advanced significantly and currently about 30% of the marketed drugs are covalent inhibitors. The numerous advant...

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Detalles Bibliográficos
Autores principales:	Sutanto, Fandi, Konstantinidou, Markella, Dömling, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557570/ https://www.ncbi.nlm.nih.gov/pubmed/33479682 http://dx.doi.org/10.1039/d0md00154f

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