Cationic drugs and COVID-19

Given the sharp spreading of COVID-19 pandemic all around the world, our attention was brought to consider that that many cationic drugs (i.e. those characterized by the presence, at physiological pH value, of one or more cationic groups, both primary, secondary, tertiary and guanidinic aminic group...

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Detalles Bibliográficos
Autores principales: Brenna, Oreste Vittore, Torretta, Sara, Pignataro, Lorenzo, Di Berardino, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557649/
https://www.ncbi.nlm.nih.gov/pubmed/33045858
http://dx.doi.org/10.1177/2058738420966078
Descripción
Sumario:Given the sharp spreading of COVID-19 pandemic all around the world, our attention was brought to consider that that many cationic drugs (i.e. those characterized by the presence, at physiological pH value, of one or more cationic groups, both primary, secondary, tertiary and guanidinic aminic groups) could have any effect in impairing SARS-CoV2 entry in the host cell. This could open to new therapeutic chances against COVID-19.

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