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The role of hypoxia-induced modulation of alveolar epithelial Na(+)- transport in hypoxemia at high altitude
Reabsorption of excess alveolar fluid is driven by vectorial Na(+)-transport across alveolar epithelium, which protects from alveolar flooding and facilitates gas exchange. Hypoxia inhibits Na(+)-reabsorption in cultured cells and in-vivo by decreasing activity of epithelial Na(+)-channels (ENaC), w...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
SAGE Publications
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557693/ https://www.ncbi.nlm.nih.gov/pubmed/33110497 http://dx.doi.org/10.1177/2045894020936662 |