Cargando…

COVID-19 Modeling in Saudi Arabia Using the Modified Susceptible-Exposed-Infectious-Recovered (SEIR) Model

The coronavirus disease 2019 (COVID-19) pandemic has created unprecedented healthcare emergencies across the globe. The World Health Organization (WHO) has proposed social distancing (SD) as a prudent measure to contain the pandemic and, hence, governments have been enacting lockdowns of varied natu...

Descripción completa

Detalles Bibliográficos
Autor principal: Ahmad, Naim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557707/
https://www.ncbi.nlm.nih.gov/pubmed/33072460
http://dx.doi.org/10.7759/cureus.10452
_version_ 1783594476657180672
author Ahmad, Naim
author_facet Ahmad, Naim
author_sort Ahmad, Naim
collection PubMed
description The coronavirus disease 2019 (COVID-19) pandemic has created unprecedented healthcare emergencies across the globe. The World Health Organization (WHO) has proposed social distancing (SD) as a prudent measure to contain the pandemic and, hence, governments have been enacting lockdowns of varied nature. These lockdowns, causing economic and social strain, warrant the development of quantitative models to optimally manage the pandemic. Similarly, extensive testing aids in early detection and isolation, hence containing the spread of the pandemic. Compartment epidemiology models have been used extensively in modeling such infectious diseases. This paper attempts to utilize the modified Susceptible-Exposed-Infectious-Recovered (SEIR) model incorporating the SD, testing, and infectiousness of exposed and infectious compartments to study the COVID-19 pandemic in Saudi Arabia. Saudi Arabia has put restrictions on the movement of people in different phases to ascertain SD. Time-dependent parameters based on the timeline of restrictions and testing in Saudi Arabia have been introduced to capture SD and testing. The arrived model has been validated through statistical tests. The [Formula: see text] (R naught), basic reproduction number, value has ranged between 0.6014 and 2.7860 with an average of 1.4904 and currently holds at 0.8952. In the absence of SD and testing measures, the model predicts the threshold herd immunity to be 69.31% and [Formula: see text] value as 3.26. Further, scenario analysis has been conducted for alleviating the SD measure. The results show that early lifting of all restrictions may undo all efforts in the containment of the COVID-19 pandemic. The outcome of results will help policymakers and medical practitioners prepare better to manage the pandemic and lockdown.
format Online
Article
Text
id pubmed-7557707
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-75577072020-10-16 COVID-19 Modeling in Saudi Arabia Using the Modified Susceptible-Exposed-Infectious-Recovered (SEIR) Model Ahmad, Naim Cureus Medical Simulation The coronavirus disease 2019 (COVID-19) pandemic has created unprecedented healthcare emergencies across the globe. The World Health Organization (WHO) has proposed social distancing (SD) as a prudent measure to contain the pandemic and, hence, governments have been enacting lockdowns of varied nature. These lockdowns, causing economic and social strain, warrant the development of quantitative models to optimally manage the pandemic. Similarly, extensive testing aids in early detection and isolation, hence containing the spread of the pandemic. Compartment epidemiology models have been used extensively in modeling such infectious diseases. This paper attempts to utilize the modified Susceptible-Exposed-Infectious-Recovered (SEIR) model incorporating the SD, testing, and infectiousness of exposed and infectious compartments to study the COVID-19 pandemic in Saudi Arabia. Saudi Arabia has put restrictions on the movement of people in different phases to ascertain SD. Time-dependent parameters based on the timeline of restrictions and testing in Saudi Arabia have been introduced to capture SD and testing. The arrived model has been validated through statistical tests. The [Formula: see text] (R naught), basic reproduction number, value has ranged between 0.6014 and 2.7860 with an average of 1.4904 and currently holds at 0.8952. In the absence of SD and testing measures, the model predicts the threshold herd immunity to be 69.31% and [Formula: see text] value as 3.26. Further, scenario analysis has been conducted for alleviating the SD measure. The results show that early lifting of all restrictions may undo all efforts in the containment of the COVID-19 pandemic. The outcome of results will help policymakers and medical practitioners prepare better to manage the pandemic and lockdown. Cureus 2020-09-14 /pmc/articles/PMC7557707/ /pubmed/33072460 http://dx.doi.org/10.7759/cureus.10452 Text en Copyright © 2020, Ahmad et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Medical Simulation
Ahmad, Naim
COVID-19 Modeling in Saudi Arabia Using the Modified Susceptible-Exposed-Infectious-Recovered (SEIR) Model
title COVID-19 Modeling in Saudi Arabia Using the Modified Susceptible-Exposed-Infectious-Recovered (SEIR) Model
title_full COVID-19 Modeling in Saudi Arabia Using the Modified Susceptible-Exposed-Infectious-Recovered (SEIR) Model
title_fullStr COVID-19 Modeling in Saudi Arabia Using the Modified Susceptible-Exposed-Infectious-Recovered (SEIR) Model
title_full_unstemmed COVID-19 Modeling in Saudi Arabia Using the Modified Susceptible-Exposed-Infectious-Recovered (SEIR) Model
title_short COVID-19 Modeling in Saudi Arabia Using the Modified Susceptible-Exposed-Infectious-Recovered (SEIR) Model
title_sort covid-19 modeling in saudi arabia using the modified susceptible-exposed-infectious-recovered (seir) model
topic Medical Simulation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557707/
https://www.ncbi.nlm.nih.gov/pubmed/33072460
http://dx.doi.org/10.7759/cureus.10452
work_keys_str_mv AT ahmadnaim covid19modelinginsaudiarabiausingthemodifiedsusceptibleexposedinfectiousrecoveredseirmodel