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Modeling Approaches Reveal New Regulatory Networks in Aspergillus fumigatus Metabolism

Systems biology approaches are extensively used to model and reverse-engineer gene regulatory networks from experimental data. Indoleamine 2,3-dioxygenases (IDOs)—belonging in the heme dioxygenase family—degrade l-tryptophan to kynurenines. These enzymes are also responsible for the de novo synthesi...

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Detalles Bibliográficos
Autores principales: Acerbi, Enzo, Hortova-Kohoutkova, Marcela, Choera, Tsokyi, Keller, Nancy, Fric, Jan, Stella, Fabio, Romani, Luigina, Zelante, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557846/
https://www.ncbi.nlm.nih.gov/pubmed/32674323
http://dx.doi.org/10.3390/jof6030108