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Recent Developments in Plasmonic Nanostructures for Metal Enhanced Fluorescence-Based Biosensing

Metal-enhanced fluorescence (MEF) is a unique phenomenon of surface plasmons, where light interacts with the metallic nanostructures and produces electromagnetic fields to enhance the sensitivity of fluorescence-based detection. In particular, this enhancement in sensing capacity is of importance to...

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Detalles Bibliográficos
Autores principales: Badshah, Mohsin Ali, Koh, Na Yoon, Zia, Abdul Wasy, Abbas, Naseem, Zahra, Zahra, Saleem, Muhammad Wajid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558009/
https://www.ncbi.nlm.nih.gov/pubmed/32899375
http://dx.doi.org/10.3390/nano10091749
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author Badshah, Mohsin Ali
Koh, Na Yoon
Zia, Abdul Wasy
Abbas, Naseem
Zahra, Zahra
Saleem, Muhammad Wajid
author_facet Badshah, Mohsin Ali
Koh, Na Yoon
Zia, Abdul Wasy
Abbas, Naseem
Zahra, Zahra
Saleem, Muhammad Wajid
author_sort Badshah, Mohsin Ali
collection PubMed
description Metal-enhanced fluorescence (MEF) is a unique phenomenon of surface plasmons, where light interacts with the metallic nanostructures and produces electromagnetic fields to enhance the sensitivity of fluorescence-based detection. In particular, this enhancement in sensing capacity is of importance to many research areas, including medical diagnostics, forensic science, and biotechnology. The article covers the basic mechanism of MEF and recent developments in plasmonic nanostructures fabrication for efficient fluorescence signal enhancement that are critically reviewed. The implications of current fluorescence-based technologies for biosensors are summarized, which are in practice to detect different analytes relevant to food control, medical diagnostics, and forensic science. Furthermore, characteristics of existing fabrication methods have been compared on the basis of their resolution, design flexibility, and throughput. The future projections emphasize exploring the potential of non-conventional materials and hybrid fabrication techniques to further enhance the sensitivity of MEF-based biosensors.
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spelling pubmed-75580092020-10-22 Recent Developments in Plasmonic Nanostructures for Metal Enhanced Fluorescence-Based Biosensing Badshah, Mohsin Ali Koh, Na Yoon Zia, Abdul Wasy Abbas, Naseem Zahra, Zahra Saleem, Muhammad Wajid Nanomaterials (Basel) Review Metal-enhanced fluorescence (MEF) is a unique phenomenon of surface plasmons, where light interacts with the metallic nanostructures and produces electromagnetic fields to enhance the sensitivity of fluorescence-based detection. In particular, this enhancement in sensing capacity is of importance to many research areas, including medical diagnostics, forensic science, and biotechnology. The article covers the basic mechanism of MEF and recent developments in plasmonic nanostructures fabrication for efficient fluorescence signal enhancement that are critically reviewed. The implications of current fluorescence-based technologies for biosensors are summarized, which are in practice to detect different analytes relevant to food control, medical diagnostics, and forensic science. Furthermore, characteristics of existing fabrication methods have been compared on the basis of their resolution, design flexibility, and throughput. The future projections emphasize exploring the potential of non-conventional materials and hybrid fabrication techniques to further enhance the sensitivity of MEF-based biosensors. MDPI 2020-09-03 /pmc/articles/PMC7558009/ /pubmed/32899375 http://dx.doi.org/10.3390/nano10091749 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Badshah, Mohsin Ali
Koh, Na Yoon
Zia, Abdul Wasy
Abbas, Naseem
Zahra, Zahra
Saleem, Muhammad Wajid
Recent Developments in Plasmonic Nanostructures for Metal Enhanced Fluorescence-Based Biosensing
title Recent Developments in Plasmonic Nanostructures for Metal Enhanced Fluorescence-Based Biosensing
title_full Recent Developments in Plasmonic Nanostructures for Metal Enhanced Fluorescence-Based Biosensing
title_fullStr Recent Developments in Plasmonic Nanostructures for Metal Enhanced Fluorescence-Based Biosensing
title_full_unstemmed Recent Developments in Plasmonic Nanostructures for Metal Enhanced Fluorescence-Based Biosensing
title_short Recent Developments in Plasmonic Nanostructures for Metal Enhanced Fluorescence-Based Biosensing
title_sort recent developments in plasmonic nanostructures for metal enhanced fluorescence-based biosensing
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558009/
https://www.ncbi.nlm.nih.gov/pubmed/32899375
http://dx.doi.org/10.3390/nano10091749
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