Cargando…

Hybrid Multimodal Imaging Synthons for Chemoselective and Efficient Biomolecule Modification with Chelator and Near-Infrared Fluorescent Cyanine Dye

The development of hybrid multimodal imaging synthons (MIS), carrying in addition to a chelator for radiometal labeling also a near-infrared (NIR) fluorescent cyanine dye was the aim of this work. The MIS should be introducible into biomolecules of choice via an efficient and chemoselective click ch...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hübner, Ralph, von Kiedrowski, Valeska, Benkert, Vanessa, Wängler, Björn, Schirrmacher, Ralf, Krämer, Roland, Wängler, Carmen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558102/ https://www.ncbi.nlm.nih.gov/pubmed/32948032 http://dx.doi.org/10.3390/ph13090250

Ejemplares similares

Side-by-Side Comparison of Five Chelators for (89)Zr-Labeling of Biomolecules: Investigation of Chemical/Radiochemical Properties and Complex Stability
por: Damerow, Helen, et al.
Publicado: (2021)

Toward Optimized (89)Zr-Immuno-PET: Side-by-Side Comparison of [(89)Zr]Zr-DFO-, [(89)Zr]Zr-3,4,3-(LI-1,2-HOPO)- and [(89)Zr]Zr-DFO*-Cetuximab for Tumor Imaging: Which Chelator Is the Most Suitable?
por: Damerow, Helen, et al.
Publicado: (2022)

Design, Synthesis, In Vitro and In Vivo Evaluation of Heterobivalent SiFAlin-Modified Peptidic Radioligands Targeting Both Integrin α(v)β(3) and the MC1 Receptor—Suitable for the Specific Visualization of Melanomas?
por: Cheng, Xia, et al.
Publicado: (2021)

Synthesis, Characterization and In Vitro Evaluation of Hybrid Monomeric Peptides Suited for Multimodal Imaging by PET/OI: Extending the Concept of Charge—Cell Binding Correlation
por: Maspero, Marco, et al.
Publicado: (2021)

α(v)β(3)-Specific Gold Nanoparticles for Fluorescence Imaging of Tumor Angiogenesis
por: Pretze, Marc, et al.
Publicado: (2021)

Photonics of Trimethine Cyanine Dyes as Probes for Biomolecules
por: Pronkin, Pavel G., et al.
Publicado: (2022)

Synthesis of a Bifunctional Cross‐Bridged Chelating Agent, Peptide Conjugation, and Comparison of (68)Ga Labeling and Complex Stability Characteristics with Established Chelators
por: Damerow, Helen, et al.
Publicado: (2022)

PESIN Conjugates for Multimodal Imaging: Can Multimerization Compensate Charge Influences on Cell Binding Properties? A Case Study †
por: Hübner, Ralph, et al.
Publicado: (2021)

The Exception That Proves the Rule: How Sodium Chelation Can Alter the Charge‐Cell Binding Correlation of Fluorescein‐Based Multimodal Imaging Agents
por: Maspero, Marco, et al.
Publicado: (2022)

Photonics of Some Monomethine Cyanine Dyes in Solutions and in Complexes with Biomolecules
por: Pronkin, Pavel G., et al.
Publicado: (2023)

Near-Infrared-II Cyanine/Polymethine Dyes, Current State and Perspective
por: Du, Yijing, et al.
Publicado: (2021)

Photouncaging of Carboxylic Acids from Cyanine Dyes with Near‐Infrared Light
por: Janeková, Hana, et al.
Publicado: (2022)

Transparent Organic Photodetector using a Near-Infrared Absorbing Cyanine Dye
por: Zhang, Hui, et al.
Publicado: (2015)

Near-Infrared Activated Cyanine Dyes As Agents for Photothermal Therapy and Diagnosis of Tumors
por: Shramova, E. I., et al.
Publicado: (2020)

Synthesis of Near-Infrared-Absorbing Anionic Heptamethine Cyanine Dyes with Trifluoromethyl Groups
por: Masuoka, Hiroki, et al.
Publicado: (2023)

Near-infrared fluorescence activation probes based on disassembly-induced emission cyanine dye
por: Hou, Tai-Cheng, et al.
Publicado: (2015)

Synthesis and Optical Properties of Near-Infrared meso-Phenyl-Substituted Symmetric Heptamethine Cyanine Dyes
por: Levitz, Andrew, et al.
Publicado: (2018)

Targeting and Imaging of Mitochondria Using Near-Infrared Cyanine Dye and Its Application to Multicolor Imaging
por: Saha, Pranab Chandra, et al.
Publicado: (2019)

Research progress of near-infrared fluorescence probes based on indole heptamethine cyanine dyes in vivo and in vitro
por: Sun, Chunlong, et al.
Publicado: (2020)

Red and Near-Infrared Absorbing Dicyanomethylene Squaraine Cyanine Dyes: Photophysicochemical Properties and Anti-Tumor Photosensitizing Effects
por: D. Martins, Tiago, et al.
Publicado: (2020)

Engineering naphthalimide-cyanine integrated near-infrared dye into ROS-responsive nanohybrids for tumor PDT/PTT/chemotherapy
por: Jin, Tongxia, et al.
Publicado: (2021)

Functional Hybrid Molecules for the Visualization of Cancer: PESIN‐Homodimers Combined with Multimodal Molecular Imaging Probes for Positron Emission Tomography and Optical Imaging: Suited for Tracking of GRPR‐Positive Malignant Tissue
por: Hübner, Ralph, et al.
Publicado: (2020)

Near-Infrared Heptamethine Cyanine Based Iron Oxide Nanoparticles for Tumor Targeted Multimodal Imaging and Photothermal Therapy
por: Lee, Sejy, et al.
Publicado: (2017)

4-Nitrophenyl activated esters are superior synthons for indirect radiofluorination of biomolecules
por: Haskali, Mohammad B., et al.
Publicado: (2020)

Site-Specific Labeling of Proteins with Near-IR Heptamethine Cyanine Dyes
por: Lin, Chen-Ming, et al.
Publicado: (2018)

Bimodal Imaging Probes for Combined PET and OI: Recent Developments and Future Directions for Hybrid Agent Development
por: Seibold, Uwe, et al.
Publicado: (2014)

Identification of a Suitable Peptidic Molecular Platform for the Development of NPY(Y(1))R‐Specific Imaging Agents
por: Krieger, Korbinian, et al.
Publicado: (2020)

Photoswitching Mechanism of Cyanine Dyes
por: Dempsey, Graham T., et al.
Publicado: (2009)

A Nonaggregating Heptamethine Cyanine for Building Brighter Labeled Biomolecules
por: Luciano, Michael P., et al.
Publicado: (2019)

(89)Zr, a Radiometal Nuclide with High Potential for Molecular Imaging with PET: Chemistry, Applications and Remaining Challenges
por: Fischer, Gabriel, et al.
Publicado: (2013)

iEDDA Conjugation Reaction in Radiometal Labeling of Peptides with (68)Ga and (64)Cu: Unexpected Findings
por: Litau, Shanna, et al.
Publicado: (2018)

Towards Radiolabeled EGFR-Specific Peptides: Alternatives to GE11
por: Judmann, Benedikt, et al.
Publicado: (2023)

(18)F-Labeled Silicon-Based Fluoride Acceptors: Potential Opportunities for Novel Positron Emitting Radiopharmaceuticals
por: Bernard-Gauthier, Vadim, et al.
Publicado: (2014)

Cyanine Dye–Nucleic Acid Interactions
por: Armitage, Bruce A.
Publicado: (2008)

Cyanine‐Flavonol Hybrids for Near‐Infrared Light‐Activated Delivery of Carbon Monoxide
por: Štacková, Lenka, et al.
Publicado: (2020)

Photochemistry with Cyanines in the Near Infrared: A Step to Chemistry 4.0 Technologies
por: Strehmel, Bernd, et al.
Publicado: (2019)

Cyanine‐Doped Lanthanide Metal–Organic Frameworks for Near‐Infrared II Bioimaging
por: Liang, Tao, et al.
Publicado: (2022)

Cucurbit[7]uril Complexation of Near-Infrared Fluorescent Azobenzene-Cyanine Conjugates
por: Kommidi, Sai Shradha Reddy, et al.
Publicado: (2022)

A Conjugate of Pentamethine Cyanine and (18)F as a Positron Emission Tomography/Near-Infrared Fluorescence Probe for Multimodality Tumor Imaging
por: An, Fei-Fei, et al.
Publicado: (2017)

Current State of Radiolabeled Heterobivalent Peptidic Ligands in Tumor Imaging and Therapy
por: Judmann, Benedikt, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_of67bb3stqatg5vhrfko1bu7v3