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Europe’s War against COVID-19: A Map of Countries’ Disease Vulnerability Using Mortality Indicators

Specific and older age-associated comorbidities increase mortality risk in severe forms of coronavirus disease (COVID-19). We matched COVID-19 comorbidities with causes of death in 28 EU countries for the total population and for the population above 65 years and applied a machine-learning-based tre...

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Autores principales: Horobet, Alexandra, Simionescu, Anca Angela, Dumitrescu, Dan Gabriel, Belascu, Lucian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558340/
https://www.ncbi.nlm.nih.gov/pubmed/32916973
http://dx.doi.org/10.3390/ijerph17186565
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author Horobet, Alexandra
Simionescu, Anca Angela
Dumitrescu, Dan Gabriel
Belascu, Lucian
author_facet Horobet, Alexandra
Simionescu, Anca Angela
Dumitrescu, Dan Gabriel
Belascu, Lucian
author_sort Horobet, Alexandra
collection PubMed
description Specific and older age-associated comorbidities increase mortality risk in severe forms of coronavirus disease (COVID-19). We matched COVID-19 comorbidities with causes of death in 28 EU countries for the total population and for the population above 65 years and applied a machine-learning-based tree clustering algorithm on shares of death for COVID-19 comorbidities and for influenza and on their growth rates between 2011 and 2016. We distributed EU countries in clusters and drew a map of the EU populations’ vulnerabilities to COVID-19 comorbidities and to influenza. Noncommunicable diseases had impressive shares of death in the EU but with substantial differences between eastern and western countries. The tree clustering algorithm accurately indicated the presence of western and eastern country clusters, with significantly different patterns of disease shares of death and growth rates. Western populations displayed higher vulnerability to malignancy, blood-related diseases, and diabetes mellitus and lower respiratory diseases, while eastern countries’ populations suffered more from ischaemic heart, cerebrovascular, and circulatory diseases. Dissimilarities between EU countries were also present when influenza was considered. The heat maps of EU populations’ vulnerability to diseases based on mortality indicators constitute the basis for more targeted health policy strategies in a collaborative effort at the EU level.
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spelling pubmed-75583402020-10-22 Europe’s War against COVID-19: A Map of Countries’ Disease Vulnerability Using Mortality Indicators Horobet, Alexandra Simionescu, Anca Angela Dumitrescu, Dan Gabriel Belascu, Lucian Int J Environ Res Public Health Article Specific and older age-associated comorbidities increase mortality risk in severe forms of coronavirus disease (COVID-19). We matched COVID-19 comorbidities with causes of death in 28 EU countries for the total population and for the population above 65 years and applied a machine-learning-based tree clustering algorithm on shares of death for COVID-19 comorbidities and for influenza and on their growth rates between 2011 and 2016. We distributed EU countries in clusters and drew a map of the EU populations’ vulnerabilities to COVID-19 comorbidities and to influenza. Noncommunicable diseases had impressive shares of death in the EU but with substantial differences between eastern and western countries. The tree clustering algorithm accurately indicated the presence of western and eastern country clusters, with significantly different patterns of disease shares of death and growth rates. Western populations displayed higher vulnerability to malignancy, blood-related diseases, and diabetes mellitus and lower respiratory diseases, while eastern countries’ populations suffered more from ischaemic heart, cerebrovascular, and circulatory diseases. Dissimilarities between EU countries were also present when influenza was considered. The heat maps of EU populations’ vulnerability to diseases based on mortality indicators constitute the basis for more targeted health policy strategies in a collaborative effort at the EU level. MDPI 2020-09-09 2020-09 /pmc/articles/PMC7558340/ /pubmed/32916973 http://dx.doi.org/10.3390/ijerph17186565 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Horobet, Alexandra
Simionescu, Anca Angela
Dumitrescu, Dan Gabriel
Belascu, Lucian
Europe’s War against COVID-19: A Map of Countries’ Disease Vulnerability Using Mortality Indicators
title Europe’s War against COVID-19: A Map of Countries’ Disease Vulnerability Using Mortality Indicators
title_full Europe’s War against COVID-19: A Map of Countries’ Disease Vulnerability Using Mortality Indicators
title_fullStr Europe’s War against COVID-19: A Map of Countries’ Disease Vulnerability Using Mortality Indicators
title_full_unstemmed Europe’s War against COVID-19: A Map of Countries’ Disease Vulnerability Using Mortality Indicators
title_short Europe’s War against COVID-19: A Map of Countries’ Disease Vulnerability Using Mortality Indicators
title_sort europe’s war against covid-19: a map of countries’ disease vulnerability using mortality indicators
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558340/
https://www.ncbi.nlm.nih.gov/pubmed/32916973
http://dx.doi.org/10.3390/ijerph17186565
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