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Kinins and Their Receptors in Infectious Diseases

Kinins and their receptors have been implicated in a series of pathological alterations, representing attractive pharmacological targets for several diseases. The present review article aims to discuss the role of the kinin system in infectious diseases. Literature data provides compelling evidence...

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Detalles Bibliográficos
Autores principales: Dagnino, Ana Paula A., Campos, Maria M., Silva, Rodrigo B. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558425/
https://www.ncbi.nlm.nih.gov/pubmed/32867272
http://dx.doi.org/10.3390/ph13090215
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author Dagnino, Ana Paula A.
Campos, Maria M.
Silva, Rodrigo B. M.
author_facet Dagnino, Ana Paula A.
Campos, Maria M.
Silva, Rodrigo B. M.
author_sort Dagnino, Ana Paula A.
collection PubMed
description Kinins and their receptors have been implicated in a series of pathological alterations, representing attractive pharmacological targets for several diseases. The present review article aims to discuss the role of the kinin system in infectious diseases. Literature data provides compelling evidence about the participation of kinins in infections caused by diverse agents, including viral, bacterial, fungal, protozoan, and helminth-related ills. It is tempting to propose that modulation of kinin actions and production might be an adjuvant strategy for management of infection-related complications.
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spelling pubmed-75584252020-10-22 Kinins and Their Receptors in Infectious Diseases Dagnino, Ana Paula A. Campos, Maria M. Silva, Rodrigo B. M. Pharmaceuticals (Basel) Review Kinins and their receptors have been implicated in a series of pathological alterations, representing attractive pharmacological targets for several diseases. The present review article aims to discuss the role of the kinin system in infectious diseases. Literature data provides compelling evidence about the participation of kinins in infections caused by diverse agents, including viral, bacterial, fungal, protozoan, and helminth-related ills. It is tempting to propose that modulation of kinin actions and production might be an adjuvant strategy for management of infection-related complications. MDPI 2020-08-27 /pmc/articles/PMC7558425/ /pubmed/32867272 http://dx.doi.org/10.3390/ph13090215 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Dagnino, Ana Paula A.
Campos, Maria M.
Silva, Rodrigo B. M.
Kinins and Their Receptors in Infectious Diseases
title Kinins and Their Receptors in Infectious Diseases
title_full Kinins and Their Receptors in Infectious Diseases
title_fullStr Kinins and Their Receptors in Infectious Diseases
title_full_unstemmed Kinins and Their Receptors in Infectious Diseases
title_short Kinins and Their Receptors in Infectious Diseases
title_sort kinins and their receptors in infectious diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558425/
https://www.ncbi.nlm.nih.gov/pubmed/32867272
http://dx.doi.org/10.3390/ph13090215
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