Synthesis, ADMET Properties, and In Vitro Antimicrobial and Antibiofilm Activity of 5-Nitro-2-thiophenecarbaldehyde N-((E)-(5-Nitrothienyl)methylidene)hydrazone (KTU-286) against Staphylococcus aureus with Defined Resistance Mechanisms

The emergence of drug-resistant Staphylococcus aureus is responsible for high morbidity and mortality worldwide. New therapeutic options are needed to fight the increasing antimicrobial resistance among S. aureus in the clinical setting. We, therefore, characterized the in silico absorption, distrib...

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Detalles Bibliográficos
Autores principales: Kavaliauskas, Povilas, Grybaite, Birute, Mickevicius, Vytautas, Petraitiene, Ruta, Grigaleviciute, Ramune, Planciuniene, Rita, Gialanella, Philip, Pockevicius, Alius, Petraitis, Vidmantas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558474/
https://www.ncbi.nlm.nih.gov/pubmed/32957471
http://dx.doi.org/10.3390/antibiotics9090612

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