Cargando…
Hif-1α Inhibitors Could Successfully Inhibit the Progression of Differentiated Thyroid Cancer in Vitro
Hypoxia-inducible factor (HIF)-1α plays an important role in cancer progression. In various cancers, including thyroid cancer, overexpression of HIF-1α is related to poor prognosis or treatment response. However, few studies have investigated the role of HIF-1α inhibition in thyroid cancer progressi...
Autores principales: | Kim, Min-Hee, Lee, Tae Hyeong, Lee, Jin Soo, Lim, Dong-Jun, Lee, Peter Chang-Whan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558478/ https://www.ncbi.nlm.nih.gov/pubmed/32847004 http://dx.doi.org/10.3390/ph13090208 |
Ejemplares similares
-
Endothelial Cell HIF-1α and HIF-2α Differentially Regulate Metastatic Success
por: Branco-Price, Cristina, et al.
Publicado: (2012) -
The Histone Methyltransferase Inhibitor BIX01294 Inhibits HIF-1α Stability and Angiogenesis
por: Oh, Su Young, et al.
Publicado: (2015) -
Expression of HIF-1α and HIF-2α correlates to biological and clinical significance in papillary thyroid carcinoma
por: Liu, Yan-Mei, et al.
Publicado: (2016) -
NQO1 inhibits proteasome-mediated degradation of HIF-1α
por: Oh, Eun-Taex, et al.
Publicado: (2016) -
Pharmacokinetic Characterization of LW6, a Novel Hypoxia-Inducible Factor-1α (HIF-1α) Inhibitor in Mice
por: Lee, Ji-Yoon, et al.
Publicado: (2021)