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Polypeptide Self-Assembled Nanoparticles as Delivery Systems for Polymyxins B and E
Polymyxins are peptide antibiotics that are highly efficient against many multidrug resistant pathogens. However, the poor stability of polymyxins in the bloodstream requires the administration of high drug doses that, in turn, can lead to polymyxin toxicity. Consequently, different delivery systems...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558620/ https://www.ncbi.nlm.nih.gov/pubmed/32933030 http://dx.doi.org/10.3390/pharmaceutics12090868 |