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One-Pot Synthesis of Thiol-Modified Liquid Crystals Conjugated Fluorescent Gold Nanoclusters

Gold nanoclusters (AuNCs) and liquid crystals (LCs) have shown great potential in nanobiotechnology applications due to their unique optical and structural properties. Herein, the hardcore of the 4-cyano biphenyl group for commonly used LCs of 4-cyano-4′-pentylbiphenyl (5CB) was utilized to synthesi...

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Autores principales: Hsu, Po-Hsuan, Yougbaré, Sibidou, Kuo, Jui-Chi, Krisnawati, Dyah Ika, Jazidie, Achmad, Nuh, Mohammad, Chou, Po-Ting, Hsiao, Yu-Cheng, Kuo, Tsung-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558681/
https://www.ncbi.nlm.nih.gov/pubmed/32899952
http://dx.doi.org/10.3390/nano10091755
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author Hsu, Po-Hsuan
Yougbaré, Sibidou
Kuo, Jui-Chi
Krisnawati, Dyah Ika
Jazidie, Achmad
Nuh, Mohammad
Chou, Po-Ting
Hsiao, Yu-Cheng
Kuo, Tsung-Rong
author_facet Hsu, Po-Hsuan
Yougbaré, Sibidou
Kuo, Jui-Chi
Krisnawati, Dyah Ika
Jazidie, Achmad
Nuh, Mohammad
Chou, Po-Ting
Hsiao, Yu-Cheng
Kuo, Tsung-Rong
author_sort Hsu, Po-Hsuan
collection PubMed
description Gold nanoclusters (AuNCs) and liquid crystals (LCs) have shown great potential in nanobiotechnology applications due to their unique optical and structural properties. Herein, the hardcore of the 4-cyano biphenyl group for commonly used LCs of 4-cyano-4′-pentylbiphenyl (5CB) was utilized to synthesize 4′-(2-mercaptoethyl)-(1,1′-biphenyl)-4-carbonitrile (TAT-12) based on Suzuki coupling and Appel reaction. The structural and optical properties of thiol-modified TAT-12 LCs were demonstrated by nuclear magnetic resonance (NMR) spectroscopy, ultraviolet-visible (UV-vis) spectroscopy and differential scanning calorimetry (DSC). By one-pot synthesis, thiol-modified TAT-12 LCs were used as the ligands to prepare fluorescent gold nanoclusters (AuNCs@TAT-12) according to the Au-S bond between AuNCs and TAT-12. The spectra of UV-vis absorption and X-ray photoelectron spectroscopy (XPS) of AuNCs@TAT-12 indicated that the core of gold of AuNCs@TAT-12 exhibited high gold oxidation states. The fluorescence of AuNCs@TAT-12 was observed with a maximum intensity at ~352 nm coming from TAT-12 on AuNCs@TAT-12 and the fluorescence quantum yield of AuNCs@TAT-12 was calculated to be 10.1%. Furthermore, the fluorescence with a maximum intensity at ~448 nm was attributed to a ligand–metal charge transfer between the ligands of TAT-12 LCs and the core of AuNCs. The image of transmission electron microscopy (TEM) further demonstrated an approximately spherical shape of AuNCs@TAT-12 with an average size of 2.3 nm. A combination of UV-vis absorption spectra, XPS spectra, fluorescence spectra and TEM image, fluorescent AuNCs@TAT-12 were successfully synthesized via one-pot synthesis. Our work provides a practical approach to the synthesis of LCs conjugated AuNCs for future applications in nanobiotechnology.
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spelling pubmed-75586812020-10-26 One-Pot Synthesis of Thiol-Modified Liquid Crystals Conjugated Fluorescent Gold Nanoclusters Hsu, Po-Hsuan Yougbaré, Sibidou Kuo, Jui-Chi Krisnawati, Dyah Ika Jazidie, Achmad Nuh, Mohammad Chou, Po-Ting Hsiao, Yu-Cheng Kuo, Tsung-Rong Nanomaterials (Basel) Article Gold nanoclusters (AuNCs) and liquid crystals (LCs) have shown great potential in nanobiotechnology applications due to their unique optical and structural properties. Herein, the hardcore of the 4-cyano biphenyl group for commonly used LCs of 4-cyano-4′-pentylbiphenyl (5CB) was utilized to synthesize 4′-(2-mercaptoethyl)-(1,1′-biphenyl)-4-carbonitrile (TAT-12) based on Suzuki coupling and Appel reaction. The structural and optical properties of thiol-modified TAT-12 LCs were demonstrated by nuclear magnetic resonance (NMR) spectroscopy, ultraviolet-visible (UV-vis) spectroscopy and differential scanning calorimetry (DSC). By one-pot synthesis, thiol-modified TAT-12 LCs were used as the ligands to prepare fluorescent gold nanoclusters (AuNCs@TAT-12) according to the Au-S bond between AuNCs and TAT-12. The spectra of UV-vis absorption and X-ray photoelectron spectroscopy (XPS) of AuNCs@TAT-12 indicated that the core of gold of AuNCs@TAT-12 exhibited high gold oxidation states. The fluorescence of AuNCs@TAT-12 was observed with a maximum intensity at ~352 nm coming from TAT-12 on AuNCs@TAT-12 and the fluorescence quantum yield of AuNCs@TAT-12 was calculated to be 10.1%. Furthermore, the fluorescence with a maximum intensity at ~448 nm was attributed to a ligand–metal charge transfer between the ligands of TAT-12 LCs and the core of AuNCs. The image of transmission electron microscopy (TEM) further demonstrated an approximately spherical shape of AuNCs@TAT-12 with an average size of 2.3 nm. A combination of UV-vis absorption spectra, XPS spectra, fluorescence spectra and TEM image, fluorescent AuNCs@TAT-12 were successfully synthesized via one-pot synthesis. Our work provides a practical approach to the synthesis of LCs conjugated AuNCs for future applications in nanobiotechnology. MDPI 2020-09-06 /pmc/articles/PMC7558681/ /pubmed/32899952 http://dx.doi.org/10.3390/nano10091755 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hsu, Po-Hsuan
Yougbaré, Sibidou
Kuo, Jui-Chi
Krisnawati, Dyah Ika
Jazidie, Achmad
Nuh, Mohammad
Chou, Po-Ting
Hsiao, Yu-Cheng
Kuo, Tsung-Rong
One-Pot Synthesis of Thiol-Modified Liquid Crystals Conjugated Fluorescent Gold Nanoclusters
title One-Pot Synthesis of Thiol-Modified Liquid Crystals Conjugated Fluorescent Gold Nanoclusters
title_full One-Pot Synthesis of Thiol-Modified Liquid Crystals Conjugated Fluorescent Gold Nanoclusters
title_fullStr One-Pot Synthesis of Thiol-Modified Liquid Crystals Conjugated Fluorescent Gold Nanoclusters
title_full_unstemmed One-Pot Synthesis of Thiol-Modified Liquid Crystals Conjugated Fluorescent Gold Nanoclusters
title_short One-Pot Synthesis of Thiol-Modified Liquid Crystals Conjugated Fluorescent Gold Nanoclusters
title_sort one-pot synthesis of thiol-modified liquid crystals conjugated fluorescent gold nanoclusters
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558681/
https://www.ncbi.nlm.nih.gov/pubmed/32899952
http://dx.doi.org/10.3390/nano10091755
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