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Mining of variables from embryo morphokinetics, blastocyst’s morphology and patient parameters: an approach to predict the live birth in the assisted reproduction service

Based on growing demand for assisted reproduction technology, improved predictive models are required to optimize in vitro fertilization/intracytoplasmatic sperm injection strategies, prioritizing single embryo transfer. There are still several obstacles to overcome for the purpose of improving assi...

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Detalles Bibliográficos
Autores principales: Chéles, Dóris Spinosa, Molin, Eloiza Adriane Dal, Rocha, José Celso, Nogueira, Marcelo Fábio Gouveia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brazilian Society of Assisted Reproduction 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558892/
https://www.ncbi.nlm.nih.gov/pubmed/32293823
http://dx.doi.org/10.5935/1518-0557.20200014
Descripción
Sumario:Based on growing demand for assisted reproduction technology, improved predictive models are required to optimize in vitro fertilization/intracytoplasmatic sperm injection strategies, prioritizing single embryo transfer. There are still several obstacles to overcome for the purpose of improving assisted reproductive success, such as intra- and inter-observer subjectivity in embryonic selection, high occurrence of multiple pregnancies, maternal and neonatal complications. Here, we compare studies that used several variables that impact the success of assisted reproduction, such as blastocyst morphology and morphokinetic aspects of embryo development as well as characteristics of the patients submitted to assisted reproduction, in order to predict embryo quality, implantation or live birth. Thereby, we emphasize the proposal of an artificial intelligence-based platform for a more objective method to predict live birth.