Noninvasive Preimplantation Genetic Testing for Aneuploidy (niPGT-A): The first Brazilian baby

Recently, a new technology known as the Noninvasive Preimplantation Genetic Testing for Aneuploidy (niPGT-A) emerged, using cell-free DNA present in the spent culture media of human blastocysts. Unlike PGT-A, in which only trophectoderm cells are used, niPGT-A reflects the ploidy state of these cell...

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Detalles Bibliográficos
Autores principales: Franco Jr., José Gonçalves, Vagnini, Laura Diniz, Petersen, Claudia Guilhermino, Renzi, Adriana, Canas, Maria C.T., Petersen, Bruna, Ricci, Juliana, Nicoletti, Andreia, Zamara, Camila, Dieamant, Felipe, Oliveira, João Batista Alcantara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brazilian Society of Assisted Reproduction 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558898/
https://www.ncbi.nlm.nih.gov/pubmed/32897670
http://dx.doi.org/10.5935/1518-0557.20200074
Descripción
Sumario:Recently, a new technology known as the Noninvasive Preimplantation Genetic Testing for Aneuploidy (niPGT-A) emerged, using cell-free DNA present in the spent culture media of human blastocysts. Unlike PGT-A, in which only trophectoderm cells are used, niPGT-A reflects the ploidy state of these cells and internal cell mass, suggesting that this new technology may be less prone to error, being more reliable than the invasive test. The aim of the present study was to report the first occurrence of childbirth following niPGT-A in Brazil.

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