Noninvasive Preimplantation Genetic Testing for Aneuploidy (niPGT-A): The first Brazilian baby

Recently, a new technology known as the Noninvasive Preimplantation Genetic Testing for Aneuploidy (niPGT-A) emerged, using cell-free DNA present in the spent culture media of human blastocysts. Unlike PGT-A, in which only trophectoderm cells are used, niPGT-A reflects the ploidy state of these cell...

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Autores principales: Franco Jr., José Gonçalves, Vagnini, Laura Diniz, Petersen, Claudia Guilhermino, Renzi, Adriana, Canas, Maria C.T., Petersen, Bruna, Ricci, Juliana, Nicoletti, Andreia, Zamara, Camila, Dieamant, Felipe, Oliveira, João Batista Alcantara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brazilian Society of Assisted Reproduction 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558898/
https://www.ncbi.nlm.nih.gov/pubmed/32897670
http://dx.doi.org/10.5935/1518-0557.20200074
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author Franco Jr., José Gonçalves
Vagnini, Laura Diniz
Petersen, Claudia Guilhermino
Renzi, Adriana
Canas, Maria C.T.
Petersen, Bruna
Ricci, Juliana
Nicoletti, Andreia
Zamara, Camila
Dieamant, Felipe
Oliveira, João Batista Alcantara
author_facet Franco Jr., José Gonçalves
Vagnini, Laura Diniz
Petersen, Claudia Guilhermino
Renzi, Adriana
Canas, Maria C.T.
Petersen, Bruna
Ricci, Juliana
Nicoletti, Andreia
Zamara, Camila
Dieamant, Felipe
Oliveira, João Batista Alcantara
author_sort Franco Jr., José Gonçalves
collection PubMed
description Recently, a new technology known as the Noninvasive Preimplantation Genetic Testing for Aneuploidy (niPGT-A) emerged, using cell-free DNA present in the spent culture media of human blastocysts. Unlike PGT-A, in which only trophectoderm cells are used, niPGT-A reflects the ploidy state of these cells and internal cell mass, suggesting that this new technology may be less prone to error, being more reliable than the invasive test. The aim of the present study was to report the first occurrence of childbirth following niPGT-A in Brazil.
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spelling pubmed-75588982020-10-20 Noninvasive Preimplantation Genetic Testing for Aneuploidy (niPGT-A): The first Brazilian baby Franco Jr., José Gonçalves Vagnini, Laura Diniz Petersen, Claudia Guilhermino Renzi, Adriana Canas, Maria C.T. Petersen, Bruna Ricci, Juliana Nicoletti, Andreia Zamara, Camila Dieamant, Felipe Oliveira, João Batista Alcantara JBRA Assist Reprod Case Report Recently, a new technology known as the Noninvasive Preimplantation Genetic Testing for Aneuploidy (niPGT-A) emerged, using cell-free DNA present in the spent culture media of human blastocysts. Unlike PGT-A, in which only trophectoderm cells are used, niPGT-A reflects the ploidy state of these cells and internal cell mass, suggesting that this new technology may be less prone to error, being more reliable than the invasive test. The aim of the present study was to report the first occurrence of childbirth following niPGT-A in Brazil. Brazilian Society of Assisted Reproduction 2020 /pmc/articles/PMC7558898/ /pubmed/32897670 http://dx.doi.org/10.5935/1518-0557.20200074 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Franco Jr., José Gonçalves
Vagnini, Laura Diniz
Petersen, Claudia Guilhermino
Renzi, Adriana
Canas, Maria C.T.
Petersen, Bruna
Ricci, Juliana
Nicoletti, Andreia
Zamara, Camila
Dieamant, Felipe
Oliveira, João Batista Alcantara
Noninvasive Preimplantation Genetic Testing for Aneuploidy (niPGT-A): The first Brazilian baby
title Noninvasive Preimplantation Genetic Testing for Aneuploidy (niPGT-A): The first Brazilian baby
title_full Noninvasive Preimplantation Genetic Testing for Aneuploidy (niPGT-A): The first Brazilian baby
title_fullStr Noninvasive Preimplantation Genetic Testing for Aneuploidy (niPGT-A): The first Brazilian baby
title_full_unstemmed Noninvasive Preimplantation Genetic Testing for Aneuploidy (niPGT-A): The first Brazilian baby
title_short Noninvasive Preimplantation Genetic Testing for Aneuploidy (niPGT-A): The first Brazilian baby
title_sort noninvasive preimplantation genetic testing for aneuploidy (nipgt-a): the first brazilian baby
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558898/
https://www.ncbi.nlm.nih.gov/pubmed/32897670
http://dx.doi.org/10.5935/1518-0557.20200074
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