Identification of New Rofecoxib-Based Cyclooxygenase-2 Inhibitors: A Bioinformatics Approach

The cyclooxygenase-2 receptor is a therapeutic target for planning potential drugs with anti-inflammatory activity. The selective cyclooxygenase-2 (COX-2) inhibitor rofecoxib was selected as a pivot molecule to perform virtual ligand-based screening from six commercial databases. We performed the se...

Descripción completa

Detalles Bibliográficos
Autores principales: Leão, Rozires P., Cruz, Josiane V., da Costa, Glauber V., Cruz, Jorddy N., Ferreira, Elenilze F. B., Silva, Raí C., de Lima, Lúcio R., Borges, Rosivaldo S., dos Santos, Gabriela B., Santos, Cleydson B. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559105/
https://www.ncbi.nlm.nih.gov/pubmed/32858871
http://dx.doi.org/10.3390/ph13090209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559105/
https://www.ncbi.nlm.nih.gov/pubmed/32858871
http://dx.doi.org/10.3390/ph13090209

Ejemplares similares