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Elucidation of the Molecular Mechanism of Wet Granulation for Pharmaceutical Standard Formulations in a High-Speed Shear Mixer Using Near-Infrared Spectroscopy

The granulation process of pharmaceutical standard formulation in a high-speed shear wet granulation (HSWG) was measured by in-line near-infrared spectroscopy (NIRS) and agitation power consumption (APC) methods. The F-1, F-2, and F-3 formulations (500 g) contained 96% w/w α-lactose monohydrate (LA)...

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Detalles Bibliográficos
Autores principales:	Omata, Ryo, Hattori, Yusuke, Sasaki, Tetsuo, Sakamoto, Tomoaki, Otsuka, Makoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559106/ https://www.ncbi.nlm.nih.gov/pubmed/32878226 http://dx.doi.org/10.3390/ph13090226

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