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Potentially Inappropriate Drug Prescribing in French Nursing Home Residents: An Observational Study
Purpose: To identify the prevalence of potentially inappropriate drug prescription in a sample of nursing home residents in France, combining explicit criteria and implicit approach and to involve pharmacists in the multi-professional process of therapeutic optimization. Methods: A cross-sectional,...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559159/ https://www.ncbi.nlm.nih.gov/pubmed/32751644 http://dx.doi.org/10.3390/pharmacy8030133 |
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author | Qassemi, Soraya Pagès, Arnaud Rouch, Laure Bismuth, Serge Stillmunkes, André Lapeyre-Mestre, Maryse McCambridge, Cécile Cool, Charlène Cestac, Philippe |
author_facet | Qassemi, Soraya Pagès, Arnaud Rouch, Laure Bismuth, Serge Stillmunkes, André Lapeyre-Mestre, Maryse McCambridge, Cécile Cool, Charlène Cestac, Philippe |
author_sort | Qassemi, Soraya |
collection | PubMed |
description | Purpose: To identify the prevalence of potentially inappropriate drug prescription in a sample of nursing home residents in France, combining explicit criteria and implicit approach and to involve pharmacists in the multi-professional process of therapeutic optimization. Methods: A cross-sectional, observational, multicenter study was conducted during a five-month period in a sample of French nursing homes. Information on drug prescription, diseases, and socio-demographic characteristics of nursing home residents was collected. For each prescription, identification of potentially inappropriate drug prescription was done, based on explicit and implicit criteria. Results: Nursing home residents were administered an average of 8.1 (SD 3.2, range 0–20) drugs per day. Nearly 87% (n = 237) of the residents had polypharmacy with five or more drugs prescribed per day. Among the 274 nursing home residents recruited from five nursing homes, 212 (77.4%) had at least one potentially inappropriate drug prescription. According to the Laroche list, 84 residents (30.7%) had at least one drug with an unfavorable benefit–harm balance. An overdosing was found for 20.1% (n = 55) of the residents. Nearly 30% (n = 82) of the residents had a drug prescribed without valid medical indication. Conclusions: This study shows that potentially inappropriate drug prescriptions are highly prevalent among nursing home residents, nevertheless pharmacists can take part in drug utilization review in collaboration with the nursing home staff. |
format | Online Article Text |
id | pubmed-7559159 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-75591592020-10-29 Potentially Inappropriate Drug Prescribing in French Nursing Home Residents: An Observational Study Qassemi, Soraya Pagès, Arnaud Rouch, Laure Bismuth, Serge Stillmunkes, André Lapeyre-Mestre, Maryse McCambridge, Cécile Cool, Charlène Cestac, Philippe Pharmacy (Basel) Article Purpose: To identify the prevalence of potentially inappropriate drug prescription in a sample of nursing home residents in France, combining explicit criteria and implicit approach and to involve pharmacists in the multi-professional process of therapeutic optimization. Methods: A cross-sectional, observational, multicenter study was conducted during a five-month period in a sample of French nursing homes. Information on drug prescription, diseases, and socio-demographic characteristics of nursing home residents was collected. For each prescription, identification of potentially inappropriate drug prescription was done, based on explicit and implicit criteria. Results: Nursing home residents were administered an average of 8.1 (SD 3.2, range 0–20) drugs per day. Nearly 87% (n = 237) of the residents had polypharmacy with five or more drugs prescribed per day. Among the 274 nursing home residents recruited from five nursing homes, 212 (77.4%) had at least one potentially inappropriate drug prescription. According to the Laroche list, 84 residents (30.7%) had at least one drug with an unfavorable benefit–harm balance. An overdosing was found for 20.1% (n = 55) of the residents. Nearly 30% (n = 82) of the residents had a drug prescribed without valid medical indication. Conclusions: This study shows that potentially inappropriate drug prescriptions are highly prevalent among nursing home residents, nevertheless pharmacists can take part in drug utilization review in collaboration with the nursing home staff. MDPI 2020-07-30 /pmc/articles/PMC7559159/ /pubmed/32751644 http://dx.doi.org/10.3390/pharmacy8030133 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Qassemi, Soraya Pagès, Arnaud Rouch, Laure Bismuth, Serge Stillmunkes, André Lapeyre-Mestre, Maryse McCambridge, Cécile Cool, Charlène Cestac, Philippe Potentially Inappropriate Drug Prescribing in French Nursing Home Residents: An Observational Study |
title | Potentially Inappropriate Drug Prescribing in French Nursing Home Residents: An Observational Study |
title_full | Potentially Inappropriate Drug Prescribing in French Nursing Home Residents: An Observational Study |
title_fullStr | Potentially Inappropriate Drug Prescribing in French Nursing Home Residents: An Observational Study |
title_full_unstemmed | Potentially Inappropriate Drug Prescribing in French Nursing Home Residents: An Observational Study |
title_short | Potentially Inappropriate Drug Prescribing in French Nursing Home Residents: An Observational Study |
title_sort | potentially inappropriate drug prescribing in french nursing home residents: an observational study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559159/ https://www.ncbi.nlm.nih.gov/pubmed/32751644 http://dx.doi.org/10.3390/pharmacy8030133 |
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