Clonal tracing reveals diverse patterns of response to immune checkpoint blockade

BACKGROUND: Immune checkpoint blockade (ICB) therapy has improved patient survival in a variety of cancers, but only a minority of cancer patients respond. Multiple studies have sought to identify general biomarkers of ICB response, but elucidating the molecular and cellular drivers of resistance fo...

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Detalles Bibliográficos
Autores principales: Gu, Shengqing Stan, Wang, Xiaoqing, Hu, Xihao, Jiang, Peng, Li, Ziyi, Traugh, Nicole, Bu, Xia, Tang, Qin, Wang, Chenfei, Zeng, Zexian, Fu, Jingxin, Meyer, Cliff, Zhang, Yi, Cejas, Paloma, Lim, Klothilda, Wang, Jin, Zhang, Wubing, Tokheim, Collin, Sahu, Avinash Das, Xing, Xiaofang, Kroger, Benjamin, Ouyang, Zhangyi, Long, Henry, Freeman, Gordon J., Brown, Myles, Liu, X. Shirley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559192/
https://www.ncbi.nlm.nih.gov/pubmed/33059736
http://dx.doi.org/10.1186/s13059-020-02166-1

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