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Bioinformatic gene analysis for potential therapeutic targets of Huntington’s disease in pre-symptomatic and symptomatic stage

BACKGROUND: Huntington’s disease (HD) is a neurodegenerative disorder characterized by psychiatric symptoms, serious motor and cognitive deficits. Certain pathological changes can already be observed in pre-symptomatic HD (pre-HD) patients; however, the underlying molecular pathogenesis is still unc...

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Detalles Bibliográficos
Autores principales:	Xiang, Chunchen, Cong, Shengri, Liang, Bin, Cong, Shuyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559361/ https://www.ncbi.nlm.nih.gov/pubmed/33054835 http://dx.doi.org/10.1186/s12967-020-02549-9

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