A novel chemical-combination screen in zebrafish identifies epigenetic small molecule candidates for the treatment of Duchenne muscular dystrophy

BACKGROUND: Duchenne muscular dystrophy (DMD) is a severe neuromuscular disorder and is one of the most common muscular dystrophies. There are currently few effective therapies to treat the disease, although many small-molecule approaches are being pursued. Certain histone deacetylase inhibitors (HD...

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Detalles Bibliográficos
Autores principales: Farr, Gist H., Morris, Melanie, Gomez, Arianna, Pham, Thao, Kilroy, Elisabeth, Parker, Elizabeth U., Said, Shery, Henry, Clarissa, Maves, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559456/
https://www.ncbi.nlm.nih.gov/pubmed/33059738
http://dx.doi.org/10.1186/s13395-020-00251-4

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