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Involvement of hpap2 and dgkA Genes in Colistin Resistance Mediated by mcr Determinants

Plasmid-mediated colistin resistance (mcr) determinants are challenging the efficacy of polymyxins against Gram-negative pathogens. Among 10 mcr genes described so far, the major determinants mcr-1 and mcr-3 are found closely linked to hpap2 or dgkA genes, encoding a hypothetical phosphatidic acid p...

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Detalles Bibliográficos
Autores principales:	Gallardo, Alejandro, Ugarte-Ruiz, María, Hernández, Marta, Miguela-Villoldo, Pedro, Rodríguez-Lázaro, David, Domínguez, Lucas, Quesada, Alberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559476/ https://www.ncbi.nlm.nih.gov/pubmed/32842668 http://dx.doi.org/10.3390/antibiotics9090531

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