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Percutaneous radiofrequency ablation is superior to hepatic resection in patients with small hepatocellular carcinoma

BACKGROUND: It is not known whether percutaneous radiofrequency ablation (PRFA) has the same treatment efficacy and fewer complications than laparoscopic resection in patients with small centrally located hepatocellular carcinoma (HCC). AIM: To compare the effectiveness of PRFA with classical laparo...

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Autores principales: Zhang, Yan-Hua, Su, Bo, Sun, Pei, Li, Ru-Meng, Peng, Xiao-Chun, Cai, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559644/
https://www.ncbi.nlm.nih.gov/pubmed/33083397
http://dx.doi.org/10.12998/wjcc.v8.i19.4380
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author Zhang, Yan-Hua
Su, Bo
Sun, Pei
Li, Ru-Meng
Peng, Xiao-Chun
Cai, Jun
author_facet Zhang, Yan-Hua
Su, Bo
Sun, Pei
Li, Ru-Meng
Peng, Xiao-Chun
Cai, Jun
author_sort Zhang, Yan-Hua
collection PubMed
description BACKGROUND: It is not known whether percutaneous radiofrequency ablation (PRFA) has the same treatment efficacy and fewer complications than laparoscopic resection in patients with small centrally located hepatocellular carcinoma (HCC). AIM: To compare the effectiveness of PRFA with classical laparoscopic resection in patients with small HCC and document the safety parameters. METHODS: In this retrospective study, 85 patients treated with hepatic resection (HR) and 90 PRFA-treated patients were enrolled in our hospital from July 2016 to July 2019. Treatment outcomes, including major complications and survival data, were evaluated. RESULTS: The results showed that minor differences existed in the baseline characteristics between the patients in the two groups. PRFA significantly increased cumulative recurrence-free survival (hazard ratio 1.048, 95%CI: 0.265–3.268) and overall survival (hazard ratio 0.126, 95%CI: 0.025–0.973); PRFA had a lower rate of major complications than HR (7.78% vs 20.0%, P < 0.05), and hospital stay was shorter in the PRFA group than in the HR group (7.8 ± 0.2 d vs 9.5 ± 0.3 d, P < 0.001). CONCLUSION: Based on the data obtained, we conclude that PRFA was superior to HR and may reduce complications and hospital stay in patients with small HCC.
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spelling pubmed-75596442020-10-19 Percutaneous radiofrequency ablation is superior to hepatic resection in patients with small hepatocellular carcinoma Zhang, Yan-Hua Su, Bo Sun, Pei Li, Ru-Meng Peng, Xiao-Chun Cai, Jun World J Clin Cases Retrospective Study BACKGROUND: It is not known whether percutaneous radiofrequency ablation (PRFA) has the same treatment efficacy and fewer complications than laparoscopic resection in patients with small centrally located hepatocellular carcinoma (HCC). AIM: To compare the effectiveness of PRFA with classical laparoscopic resection in patients with small HCC and document the safety parameters. METHODS: In this retrospective study, 85 patients treated with hepatic resection (HR) and 90 PRFA-treated patients were enrolled in our hospital from July 2016 to July 2019. Treatment outcomes, including major complications and survival data, were evaluated. RESULTS: The results showed that minor differences existed in the baseline characteristics between the patients in the two groups. PRFA significantly increased cumulative recurrence-free survival (hazard ratio 1.048, 95%CI: 0.265–3.268) and overall survival (hazard ratio 0.126, 95%CI: 0.025–0.973); PRFA had a lower rate of major complications than HR (7.78% vs 20.0%, P < 0.05), and hospital stay was shorter in the PRFA group than in the HR group (7.8 ± 0.2 d vs 9.5 ± 0.3 d, P < 0.001). CONCLUSION: Based on the data obtained, we conclude that PRFA was superior to HR and may reduce complications and hospital stay in patients with small HCC. Baishideng Publishing Group Inc 2020-10-06 2020-10-06 /pmc/articles/PMC7559644/ /pubmed/33083397 http://dx.doi.org/10.12998/wjcc.v8.i19.4380 Text en ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Retrospective Study
Zhang, Yan-Hua
Su, Bo
Sun, Pei
Li, Ru-Meng
Peng, Xiao-Chun
Cai, Jun
Percutaneous radiofrequency ablation is superior to hepatic resection in patients with small hepatocellular carcinoma
title Percutaneous radiofrequency ablation is superior to hepatic resection in patients with small hepatocellular carcinoma
title_full Percutaneous radiofrequency ablation is superior to hepatic resection in patients with small hepatocellular carcinoma
title_fullStr Percutaneous radiofrequency ablation is superior to hepatic resection in patients with small hepatocellular carcinoma
title_full_unstemmed Percutaneous radiofrequency ablation is superior to hepatic resection in patients with small hepatocellular carcinoma
title_short Percutaneous radiofrequency ablation is superior to hepatic resection in patients with small hepatocellular carcinoma
title_sort percutaneous radiofrequency ablation is superior to hepatic resection in patients with small hepatocellular carcinoma
topic Retrospective Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559644/
https://www.ncbi.nlm.nih.gov/pubmed/33083397
http://dx.doi.org/10.12998/wjcc.v8.i19.4380
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