Cargando…

Liver injury in COVID-19: A minireview

In December 2019, an outbreak of unexplained pneumonia was reported in Wuhan, China. The World Health Organization officially named this disease as novel coronavirus disease 2019 (COVID-19). Liver injury was observed in patients with COVID-19, and its severity varied depending on disease severity, g...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Jian-Nan, Fan, Ying, Wu, Shuo-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559647/
https://www.ncbi.nlm.nih.gov/pubmed/33083389
http://dx.doi.org/10.12998/wjcc.v8.i19.4303
_version_ 1783594908297199616
author Zhao, Jian-Nan
Fan, Ying
Wu, Shuo-Dong
author_facet Zhao, Jian-Nan
Fan, Ying
Wu, Shuo-Dong
author_sort Zhao, Jian-Nan
collection PubMed
description In December 2019, an outbreak of unexplained pneumonia was reported in Wuhan, China. The World Health Organization officially named this disease as novel coronavirus disease 2019 (COVID-19). Liver injury was observed in patients with COVID-19, and its severity varied depending on disease severity, geographical area, and patient age. Systemic inflammatory response, immune damage, ischemia-reperfusion injury, viral direct damage, drug induce, mechanical ventilation, and underlying diseases may contribute to liver injury. Although, in most cases, mild liver dysfunction is observed, which is usually temporary and does not require special treatment, the importance of monitoring liver injury should be emphasized for doctors. The risk of COVID-19 infection of liver transplantation recipients caused more and more concerns. In this article, we aimed to review the available literature on liver injury in COVID-19 to highlight the importance of monitoring and treating liver injury in COVID-19.
format Online
Article
Text
id pubmed-7559647
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Baishideng Publishing Group Inc
record_format MEDLINE/PubMed
spelling pubmed-75596472020-10-19 Liver injury in COVID-19: A minireview Zhao, Jian-Nan Fan, Ying Wu, Shuo-Dong World J Clin Cases Minireviews In December 2019, an outbreak of unexplained pneumonia was reported in Wuhan, China. The World Health Organization officially named this disease as novel coronavirus disease 2019 (COVID-19). Liver injury was observed in patients with COVID-19, and its severity varied depending on disease severity, geographical area, and patient age. Systemic inflammatory response, immune damage, ischemia-reperfusion injury, viral direct damage, drug induce, mechanical ventilation, and underlying diseases may contribute to liver injury. Although, in most cases, mild liver dysfunction is observed, which is usually temporary and does not require special treatment, the importance of monitoring liver injury should be emphasized for doctors. The risk of COVID-19 infection of liver transplantation recipients caused more and more concerns. In this article, we aimed to review the available literature on liver injury in COVID-19 to highlight the importance of monitoring and treating liver injury in COVID-19. Baishideng Publishing Group Inc 2020-10-06 2020-10-06 /pmc/articles/PMC7559647/ /pubmed/33083389 http://dx.doi.org/10.12998/wjcc.v8.i19.4303 Text en ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Minireviews
Zhao, Jian-Nan
Fan, Ying
Wu, Shuo-Dong
Liver injury in COVID-19: A minireview
title Liver injury in COVID-19: A minireview
title_full Liver injury in COVID-19: A minireview
title_fullStr Liver injury in COVID-19: A minireview
title_full_unstemmed Liver injury in COVID-19: A minireview
title_short Liver injury in COVID-19: A minireview
title_sort liver injury in covid-19: a minireview
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559647/
https://www.ncbi.nlm.nih.gov/pubmed/33083389
http://dx.doi.org/10.12998/wjcc.v8.i19.4303
work_keys_str_mv AT zhaojiannan liverinjuryincovid19aminireview
AT fanying liverinjuryincovid19aminireview
AT wushuodong liverinjuryincovid19aminireview