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CPAnet Registry—An International Chronic Pulmonary Aspergillosis Registry
Chronic pulmonary aspergillosis (CPA) is a chronic fungal infection of the lung associated with high morbidity and mortality. The CPA Research network (CPAnet) registry established in 2018 is an international multicenter collaboration aiming to improve CPA knowledge and patient care. This study’s ai...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559693/ https://www.ncbi.nlm.nih.gov/pubmed/32610566 http://dx.doi.org/10.3390/jof6030096 |
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author | Laursen, Christian B. Davidsen, Jesper Rømhild Van Acker, Lander Salzer, Helmut J.F. Seidel, Danila Cornely, Oliver A. Hoenigl, Martin Alastruey-Izquierdo, Ana Hennequin, Christophe Godet, Cendrine Barac, Aleksandra Flick, Holger Munteanu, Oxana Van Braeckel, Eva |
author_facet | Laursen, Christian B. Davidsen, Jesper Rømhild Van Acker, Lander Salzer, Helmut J.F. Seidel, Danila Cornely, Oliver A. Hoenigl, Martin Alastruey-Izquierdo, Ana Hennequin, Christophe Godet, Cendrine Barac, Aleksandra Flick, Holger Munteanu, Oxana Van Braeckel, Eva |
author_sort | Laursen, Christian B. |
collection | PubMed |
description | Chronic pulmonary aspergillosis (CPA) is a chronic fungal infection of the lung associated with high morbidity and mortality. The CPA Research network (CPAnet) registry established in 2018 is an international multicenter collaboration aiming to improve CPA knowledge and patient care. This study’s aim was to describe the data collection process and content of CPAnet registry with preliminary clinical data. In the CPAnet registry, clinical data are collected through a web-based questionnaire. Data include CPA phenotype, comorbidities, treatment, outcome, and follow-up from several international centers. An exemplary descriptive analysis was performed on 74 patients, who were registered online before April 2020. CPA patients were predominantly (72%) male, 39% had chronic obstructive pulmonary disease, and 68% had a history of smoking. Chronic cavitary pulmonary aspergillosis was the most common CPA subtype (62%). In 32 patients (52%), voriconazole was the preferred first-line therapy. The multicenter multinational CPAnet registry is a valuable approach to gather comprehensive data on a large study population and reflects real-world clinical practice rather than focusing on specific patient populations in more specialized centers. Additional CPA reference centers are being encouraged to join this promising clinical research collaboration. |
format | Online Article Text |
id | pubmed-7559693 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-75596932020-10-29 CPAnet Registry—An International Chronic Pulmonary Aspergillosis Registry Laursen, Christian B. Davidsen, Jesper Rømhild Van Acker, Lander Salzer, Helmut J.F. Seidel, Danila Cornely, Oliver A. Hoenigl, Martin Alastruey-Izquierdo, Ana Hennequin, Christophe Godet, Cendrine Barac, Aleksandra Flick, Holger Munteanu, Oxana Van Braeckel, Eva J Fungi (Basel) Article Chronic pulmonary aspergillosis (CPA) is a chronic fungal infection of the lung associated with high morbidity and mortality. The CPA Research network (CPAnet) registry established in 2018 is an international multicenter collaboration aiming to improve CPA knowledge and patient care. This study’s aim was to describe the data collection process and content of CPAnet registry with preliminary clinical data. In the CPAnet registry, clinical data are collected through a web-based questionnaire. Data include CPA phenotype, comorbidities, treatment, outcome, and follow-up from several international centers. An exemplary descriptive analysis was performed on 74 patients, who were registered online before April 2020. CPA patients were predominantly (72%) male, 39% had chronic obstructive pulmonary disease, and 68% had a history of smoking. Chronic cavitary pulmonary aspergillosis was the most common CPA subtype (62%). In 32 patients (52%), voriconazole was the preferred first-line therapy. The multicenter multinational CPAnet registry is a valuable approach to gather comprehensive data on a large study population and reflects real-world clinical practice rather than focusing on specific patient populations in more specialized centers. Additional CPA reference centers are being encouraged to join this promising clinical research collaboration. MDPI 2020-06-29 /pmc/articles/PMC7559693/ /pubmed/32610566 http://dx.doi.org/10.3390/jof6030096 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Laursen, Christian B. Davidsen, Jesper Rømhild Van Acker, Lander Salzer, Helmut J.F. Seidel, Danila Cornely, Oliver A. Hoenigl, Martin Alastruey-Izquierdo, Ana Hennequin, Christophe Godet, Cendrine Barac, Aleksandra Flick, Holger Munteanu, Oxana Van Braeckel, Eva CPAnet Registry—An International Chronic Pulmonary Aspergillosis Registry |
title | CPAnet Registry—An International Chronic Pulmonary Aspergillosis Registry |
title_full | CPAnet Registry—An International Chronic Pulmonary Aspergillosis Registry |
title_fullStr | CPAnet Registry—An International Chronic Pulmonary Aspergillosis Registry |
title_full_unstemmed | CPAnet Registry—An International Chronic Pulmonary Aspergillosis Registry |
title_short | CPAnet Registry—An International Chronic Pulmonary Aspergillosis Registry |
title_sort | cpanet registry—an international chronic pulmonary aspergillosis registry |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559693/ https://www.ncbi.nlm.nih.gov/pubmed/32610566 http://dx.doi.org/10.3390/jof6030096 |
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