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Tanshinone IIA attenuates neuroinflammation via inhibiting RAGE/NF-κB signaling pathway in vivo and in vitro

BACKGROUND: Glial activation and neuroinflammation play a crucial role in the pathogenesis and development of Alzheimer’s disease (AD). The receptor for advanced glycation end products (RAGE)-mediated signaling pathway is related to amyloid beta (Aβ)-induced neuroinflammation. This study aimed to in...

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Detalles Bibliográficos
Autores principales: Ding, Bo, Lin, Chengheng, Liu, Qian, He, Yingying, Ruganzu, John Bosco, Jin, Hui, Peng, Xiaoqian, Ji, Shengfeng, Ma, Yanbing, Yang, Weina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559789/
https://www.ncbi.nlm.nih.gov/pubmed/33054814
http://dx.doi.org/10.1186/s12974-020-01981-4

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