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Tanshinone IIA attenuates neuroinflammation via inhibiting RAGE/NF-κB signaling pathway in vivo and in vitro
BACKGROUND: Glial activation and neuroinflammation play a crucial role in the pathogenesis and development of Alzheimer’s disease (AD). The receptor for advanced glycation end products (RAGE)-mediated signaling pathway is related to amyloid beta (Aβ)-induced neuroinflammation. This study aimed to in...
Autores principales: | Ding, Bo, Lin, Chengheng, Liu, Qian, He, Yingying, Ruganzu, John Bosco, Jin, Hui, Peng, Xiaoqian, Ji, Shengfeng, Ma, Yanbing, Yang, Weina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559789/ https://www.ncbi.nlm.nih.gov/pubmed/33054814 http://dx.doi.org/10.1186/s12974-020-01981-4 |
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