Cargando…

In Silico Identification of Novel Immunogenic Secreted Proteins of Mycoplasma bovis from Secretome Data and Experimental Verification

Mycoplasma bovis is a major pathogen, responsible for bovine respiratory diseases worldwide. The present lack of effective control measures leaves cattle owners at considerable perpetual risk of M. bovis outbreaks. In this study, we identified M. bovis secreted immunogenic proteins in silico as pote...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shirani, Ihsanullah, Zhang, Hui, Zhao, Gang, Lu, Siyi, Marawan, Marawan A, Dawood, Ali, Chen, Yingyu, Chen, Xi, Chen, Jianguo, Hu, Changmin, Chen, Huanchun, Guo, Aizhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559824/ https://www.ncbi.nlm.nih.gov/pubmed/32967149 http://dx.doi.org/10.3390/pathogens9090770

Ejemplares similares

Comparative Secretome Analyses of Mycoplasma bovis Virulent and Attenuated Strains Revealed MbovP0145 as a Promising Diagnostic Biomarker
por: Zhang, Hui, et al.
Publicado: (2021)

Novel Secreted Protein of Mycoplasma bovis MbovP280 Induces Macrophage Apoptosis Through CRYAB
por: Zhao, Gang, et al.
Publicado: (2021)

Characterization of BoHV-1 gG-/tk-/gE- Mutant in Differential Protein Expression, Virulence, and Immunity
por: Marawan, Marawan A., et al.
Publicado: (2021)

The attenuated Mycoplasma bovis strain promotes apoptosis of bovine macrophages by upregulation of CHOP expression
por: Zhang, Hui, et al.
Publicado: (2022)

Mycoplasmas as Host Pantropic and Specific Pathogens: Clinical Implications, Gene Transfer, Virulence Factors, and Future Perspectives
por: Dawood, Ali, et al.
Publicado: (2022)

Corrigendum: mycoplasmas as host pantropic and specific pathogens: clinical implications, gene transfer, virulence factors, and future perspectives
por: Dawood, Ali, et al.
Publicado: (2022)

Comparative Geno-Plasticity Analysis of Mycoplasma bovis HB0801 (Chinese Isolate)
por: Qi, Jingjing, et al.
Publicado: (2012)

Calves Infected with Virulent and Attenuated Mycoplasma bovis Strains Have Upregulated Th17 Inflammatory and Th1 Protective Responses, Respectively
por: Chao, Jin, et al.
Publicado: (2019)

Mbov_0503 Encodes a Novel Cytoadhesin that Facilitates Mycoplasma bovis Interaction with Tight Junctions
por: Zhu, Xifang, et al.
Publicado: (2020)

Mycoplasma bovis MBOV_RS02825 Encodes a Secretory Nuclease Associated with Cytotoxicity
por: Zhang, Hui, et al.
Publicado: (2016)

Mycoplasma bovis NADH oxidase functions as both a NADH oxidizing and O(2) reducing enzyme and an adhesin
por: Zhao, Gang, et al.
Publicado: (2017)

Annexin A2 regulates Mycoplasma bovis adhesion and invasion to embryo bovine lung cells affecting molecular expression essential to inflammatory response
por: Zhang, Hui, et al.
Publicado: (2022)

Proteomics identification and characterization of MbovP730 as a potential DIVA antigen of Mycoplasma bovis
por: Khan, Farhan Anwar, et al.
Publicado: (2017)

Comparative Genomics of Mycoplasma bovis Strains Reveals That Decreased Virulence with Increasing Passages Might Correlate with Potential Virulence-Related Factors
por: Rasheed, Muhammad A., et al.
Publicado: (2017)

Regularity of Toll-Like Receptors in Bovine Mammary Epithelial Cells Induced by Mycoplasma bovis
por: Yang, Jinghan, et al.
Publicado: (2022)

An emerging role for cyclic dinucleotide phosphodiesterase and nanoRNase activities in Mycoplasma bovis: Securing survival in cell culture
por: Zhu, Xifang, et al.
Publicado: (2020)

Bovine Leukaemia Virus: Current Epidemiological Circumstance and Future Prospective
por: Marawan, Marawan A., et al.
Publicado: (2021)

Immunoproteomic identification of MbovP579, a promising diagnostic biomarker for serological detection of Mycoplasma bovis infection
por: Khan, Farhan Anwar, et al.
Publicado: (2016)

The Safety and Protective Efficacy Evaluation of an Attenuated M. bovis–BoHV-1 Bivalent Vaccine in Rabbits
por: Zhang, Sen, et al.
Publicado: (2023)

Identification of Unique Key miRNAs, TFs, and mRNAs in Virulent MTB Infection Macrophages by Network Analysis
por: Zhu, Tingting, et al.
Publicado: (2021)

TrmFO, a Fibronectin-Binding Adhesin of Mycoplasma bovis
por: Guo, Yongpeng, et al.
Publicado: (2017)

Molecular Characterization of UL50 (dUTPase) Gene of Bovine Herpes Virus 1
por: Shahin, Farzana, et al.
Publicado: (2023)

Secreted MbovP0145 Promotes IL-8 Expression through Its Interactive β-Actin and MAPK Activation and Contributes to Neutrophil Migration
por: Lu, Doukun, et al.
Publicado: (2021)

Bovine herpesvirus 1 tegument protein UL21 plays critical roles in viral secondary envelopment and cell-to-cell spreading
por: Shahin, Farzana, et al.
Publicado: (2017)

Immune Evasion of Mycoplasma bovis
por: Askar, Hussam, et al.
Publicado: (2021)

Novel mycoplasma nucleomodulin MbovP475 decreased cell viability by regulating expression of CRYAB and MCF2L2
por: Zhao, Gang, et al.
Publicado: (2022)

Evaluation of Antiviral Activity of Ivermectin against Infectious Bovine Rhinotracheitis Virus in Rabbit Model
por: Wang, Chen, et al.
Publicado: (2023)

Prevalence of bovine astroviruses and their genotypes in sampled Chinese calves with and without diarrhoea
por: Zhu, Jie, et al.
Publicado: (2021)

MicroRNA Profile of MA-104 Cell Line Associated With the Pathogenesis of Bovine Rotavirus Strain Circulated in Chinese Calves
por: Elkady, Gehad, et al.
Publicado: (2022)

A bovine herpesvirus 1 pUL51 deletion mutant shows impaired viral growth in vitro and reduced virulence in rabbits
por: Raza, Sohail, et al.
Publicado: (2016)

Mycoplasma bovis Mastitis
por: Gelgie, Aga E., et al.
Publicado: (2022)

Upregulation of Cytokines and Differentiation of Th17 and Treg by Dendritic Cells: Central Role of Prostaglandin E2 Induced by Mycobacterium bovis
por: Liu, Han, et al.
Publicado: (2020)

Ivermectin Inhibits Bovine Herpesvirus 1 DNA Polymerase Nuclear Import and Interferes With Viral Replication
por: Raza, Sohail, et al.
Publicado: (2020)

Extracellular DNA: A Nutritional Trigger of Mycoplasma bovis Cytotoxicity
por: Zhu, Xifang, et al.
Publicado: (2019)

Epidemiological Survey and Risk Factor Analysis of 14 Potential Pathogens in Golden Snub-Nosed Monkeys at Shennongjia National Nature Reserve, China
por: Qi, Mingpu, et al.
Publicado: (2023)

The presence of Mycoplasma bovis in colostrum
por: Gille, Linde, et al.
Publicado: (2020)

The Role of N(6)-Methyladenosine in Inflammatory Diseases
por: Xu, Haojun, et al.
Publicado: (2022)

Sensitive and Specific Detection of Lumpy Skin Disease Virus in Cattle by CRISPR-Cas12a Fluorescent Assay Coupled with Recombinase Polymerase Amplification
por: Jiang, Chuanwen, et al.
Publicado: (2022)

Gut microbiome variations in Rhinopithecus roxellanae caused by changes in the environment
por: Zhao, Gang, et al.
Publicado: (2023)

Genes Found Essential in Other Mycoplasmas Are Dispensable in Mycoplasma bovis
por: Sharma, Shukriti, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_7kj8vv0fjjh38dchjin036ce4i