Epithelial WNT2B and Desert Hedgehog Are Necessary for Human Colonoid Regeneration after Bacterial Cytotoxin Injury

Intestinal regeneration and crypt hyperplasia after radiation or pathogen injury relies on Wnt signaling to stimulate stem cell proliferation. Mesenchymal Wnts are essential for homeostasis and regeneration in mice, but the role of epithelial Wnts remains largely uncharacterized. Using the enterohem...

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Detalles Bibliográficos
Autores principales: In, Julie G., Yin, Jianyi, Atanga, Roger, Doucet, Michele, Cole, Robert N., DeVine, Lauren, Donowitz, Mark, Zachos, Nicholas C., Blutt, Sarah E., Estes, Mary K., Kovbasnjuk, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559866/
https://www.ncbi.nlm.nih.gov/pubmed/33089106
http://dx.doi.org/10.1016/j.isci.2020.101618

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