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Successful Management of Hypothermic Cardiopulmonary Bypass in a Malignant Hyperthermia Susceptible Patient
Malignant hyperthermia (MH) is a potentially lethal reaction in those that are genetically predisposed, frequently triggered by inhaled anesthetics. MH is often difficult to diagnose because it is accompanied by signs and symptoms that are shared with other disorders. The diagnosis is further obscur...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559943/ https://www.ncbi.nlm.nih.gov/pubmed/32687103 http://dx.doi.org/10.4103/aca.ACA_245_18 |
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author | Agarwal, Shvetank Graham, Kevin Kigwana, Simon Castresana, Manuel |
author_facet | Agarwal, Shvetank Graham, Kevin Kigwana, Simon Castresana, Manuel |
author_sort | Agarwal, Shvetank |
collection | PubMed |
description | Malignant hyperthermia (MH) is a potentially lethal reaction in those that are genetically predisposed, frequently triggered by inhaled anesthetics. MH is often difficult to diagnose because it is accompanied by signs and symptoms that are shared with other disorders. The diagnosis is further obscured in cardiac surgical patients, as the signs of MH can be masked by the cardiopulmonary bypass circuit (CPB) and the use of induced hypothermia. In this case-report, we describe the successful anesthetic management of a 65-year-old MH-susceptible female, confirmed via caffeine halothane contracture test, with aortic regurgitation and ascending aortic dilatation who underwent a Bentall procedure. We have also identified certain key measures for the safe anesthetic management of these patients. |
format | Online Article Text |
id | pubmed-7559943 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-75599432020-10-20 Successful Management of Hypothermic Cardiopulmonary Bypass in a Malignant Hyperthermia Susceptible Patient Agarwal, Shvetank Graham, Kevin Kigwana, Simon Castresana, Manuel Ann Card Anaesth Case Report Malignant hyperthermia (MH) is a potentially lethal reaction in those that are genetically predisposed, frequently triggered by inhaled anesthetics. MH is often difficult to diagnose because it is accompanied by signs and symptoms that are shared with other disorders. The diagnosis is further obscured in cardiac surgical patients, as the signs of MH can be masked by the cardiopulmonary bypass circuit (CPB) and the use of induced hypothermia. In this case-report, we describe the successful anesthetic management of a 65-year-old MH-susceptible female, confirmed via caffeine halothane contracture test, with aortic regurgitation and ascending aortic dilatation who underwent a Bentall procedure. We have also identified certain key measures for the safe anesthetic management of these patients. Wolters Kluwer - Medknow 2020 2020-07-17 /pmc/articles/PMC7559943/ /pubmed/32687103 http://dx.doi.org/10.4103/aca.ACA_245_18 Text en Copyright: © 2020 Annals of Cardiac Anaesthesia http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Agarwal, Shvetank Graham, Kevin Kigwana, Simon Castresana, Manuel Successful Management of Hypothermic Cardiopulmonary Bypass in a Malignant Hyperthermia Susceptible Patient |
title | Successful Management of Hypothermic Cardiopulmonary Bypass in a Malignant Hyperthermia Susceptible Patient |
title_full | Successful Management of Hypothermic Cardiopulmonary Bypass in a Malignant Hyperthermia Susceptible Patient |
title_fullStr | Successful Management of Hypothermic Cardiopulmonary Bypass in a Malignant Hyperthermia Susceptible Patient |
title_full_unstemmed | Successful Management of Hypothermic Cardiopulmonary Bypass in a Malignant Hyperthermia Susceptible Patient |
title_short | Successful Management of Hypothermic Cardiopulmonary Bypass in a Malignant Hyperthermia Susceptible Patient |
title_sort | successful management of hypothermic cardiopulmonary bypass in a malignant hyperthermia susceptible patient |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559943/ https://www.ncbi.nlm.nih.gov/pubmed/32687103 http://dx.doi.org/10.4103/aca.ACA_245_18 |
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