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Successful Management of Hypothermic Cardiopulmonary Bypass in a Malignant Hyperthermia Susceptible Patient

Malignant hyperthermia (MH) is a potentially lethal reaction in those that are genetically predisposed, frequently triggered by inhaled anesthetics. MH is often difficult to diagnose because it is accompanied by signs and symptoms that are shared with other disorders. The diagnosis is further obscur...

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Autores principales: Agarwal, Shvetank, Graham, Kevin, Kigwana, Simon, Castresana, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559943/
https://www.ncbi.nlm.nih.gov/pubmed/32687103
http://dx.doi.org/10.4103/aca.ACA_245_18
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author Agarwal, Shvetank
Graham, Kevin
Kigwana, Simon
Castresana, Manuel
author_facet Agarwal, Shvetank
Graham, Kevin
Kigwana, Simon
Castresana, Manuel
author_sort Agarwal, Shvetank
collection PubMed
description Malignant hyperthermia (MH) is a potentially lethal reaction in those that are genetically predisposed, frequently triggered by inhaled anesthetics. MH is often difficult to diagnose because it is accompanied by signs and symptoms that are shared with other disorders. The diagnosis is further obscured in cardiac surgical patients, as the signs of MH can be masked by the cardiopulmonary bypass circuit (CPB) and the use of induced hypothermia. In this case-report, we describe the successful anesthetic management of a 65-year-old MH-susceptible female, confirmed via caffeine halothane contracture test, with aortic regurgitation and ascending aortic dilatation who underwent a Bentall procedure. We have also identified certain key measures for the safe anesthetic management of these patients.
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spelling pubmed-75599432020-10-20 Successful Management of Hypothermic Cardiopulmonary Bypass in a Malignant Hyperthermia Susceptible Patient Agarwal, Shvetank Graham, Kevin Kigwana, Simon Castresana, Manuel Ann Card Anaesth Case Report Malignant hyperthermia (MH) is a potentially lethal reaction in those that are genetically predisposed, frequently triggered by inhaled anesthetics. MH is often difficult to diagnose because it is accompanied by signs and symptoms that are shared with other disorders. The diagnosis is further obscured in cardiac surgical patients, as the signs of MH can be masked by the cardiopulmonary bypass circuit (CPB) and the use of induced hypothermia. In this case-report, we describe the successful anesthetic management of a 65-year-old MH-susceptible female, confirmed via caffeine halothane contracture test, with aortic regurgitation and ascending aortic dilatation who underwent a Bentall procedure. We have also identified certain key measures for the safe anesthetic management of these patients. Wolters Kluwer - Medknow 2020 2020-07-17 /pmc/articles/PMC7559943/ /pubmed/32687103 http://dx.doi.org/10.4103/aca.ACA_245_18 Text en Copyright: © 2020 Annals of Cardiac Anaesthesia http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Agarwal, Shvetank
Graham, Kevin
Kigwana, Simon
Castresana, Manuel
Successful Management of Hypothermic Cardiopulmonary Bypass in a Malignant Hyperthermia Susceptible Patient
title Successful Management of Hypothermic Cardiopulmonary Bypass in a Malignant Hyperthermia Susceptible Patient
title_full Successful Management of Hypothermic Cardiopulmonary Bypass in a Malignant Hyperthermia Susceptible Patient
title_fullStr Successful Management of Hypothermic Cardiopulmonary Bypass in a Malignant Hyperthermia Susceptible Patient
title_full_unstemmed Successful Management of Hypothermic Cardiopulmonary Bypass in a Malignant Hyperthermia Susceptible Patient
title_short Successful Management of Hypothermic Cardiopulmonary Bypass in a Malignant Hyperthermia Susceptible Patient
title_sort successful management of hypothermic cardiopulmonary bypass in a malignant hyperthermia susceptible patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559943/
https://www.ncbi.nlm.nih.gov/pubmed/32687103
http://dx.doi.org/10.4103/aca.ACA_245_18
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