Can Bioactive Lipid Arachidonic Acid Prevent and Ameliorate COVID-19?

It is proposed that the bioactive lipid, arachidonic acid (AA, 20:4 n-6), can inactivate severe acute respiratory syndrome(SARS-CoV-2), facilitate M1 and M2 macrophage generation, suppress inflammation, prevent vascular endothelial cell damage, and regulate inflammation resolution processes based on...

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Detalles Bibliográficos
Autor principal: Das, Undurti N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560027/
https://www.ncbi.nlm.nih.gov/pubmed/32825011
http://dx.doi.org/10.3390/medicina56090418
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author Das, Undurti N.
author_facet Das, Undurti N.
author_sort Das, Undurti N.
collection PubMed
description It is proposed that the bioactive lipid, arachidonic acid (AA, 20:4 n-6), can inactivate severe acute respiratory syndrome(SARS-CoV-2), facilitate M1 and M2 macrophage generation, suppress inflammation, prevent vascular endothelial cell damage, and regulate inflammation resolution processes based on the timely formation of prostaglandin E2 (PGE2) and lipoxin A4 (LXA4) based on the context. Thus, AA may be useful both to prevent and manage coronavrus disease-2019(COVID-19).
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spelling pubmed-75600272020-10-22 Can Bioactive Lipid Arachidonic Acid Prevent and Ameliorate COVID-19? Das, Undurti N. Medicina (Kaunas) Commentary It is proposed that the bioactive lipid, arachidonic acid (AA, 20:4 n-6), can inactivate severe acute respiratory syndrome(SARS-CoV-2), facilitate M1 and M2 macrophage generation, suppress inflammation, prevent vascular endothelial cell damage, and regulate inflammation resolution processes based on the timely formation of prostaglandin E2 (PGE2) and lipoxin A4 (LXA4) based on the context. Thus, AA may be useful both to prevent and manage coronavrus disease-2019(COVID-19). MDPI 2020-08-19 /pmc/articles/PMC7560027/ /pubmed/32825011 http://dx.doi.org/10.3390/medicina56090418 Text en © 2020 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Commentary
Das, Undurti N.
Can Bioactive Lipid Arachidonic Acid Prevent and Ameliorate COVID-19?
title Can Bioactive Lipid Arachidonic Acid Prevent and Ameliorate COVID-19?
title_full Can Bioactive Lipid Arachidonic Acid Prevent and Ameliorate COVID-19?
title_fullStr Can Bioactive Lipid Arachidonic Acid Prevent and Ameliorate COVID-19?
title_full_unstemmed Can Bioactive Lipid Arachidonic Acid Prevent and Ameliorate COVID-19?
title_short Can Bioactive Lipid Arachidonic Acid Prevent and Ameliorate COVID-19?
title_sort can bioactive lipid arachidonic acid prevent and ameliorate covid-19?
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560027/
https://www.ncbi.nlm.nih.gov/pubmed/32825011
http://dx.doi.org/10.3390/medicina56090418
work_keys_str_mv AT dasundurtin canbioactivelipidarachidonicacidpreventandamelioratecovid19

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