Cargando…

Impact of COVID-19 on people living with HIV: A review

There is great concern about the impact of COVID-19 among the nearly 40 million people living with HIV (PLWH) worldwide. In this review, we surveyed current literature and found no evidence of higher prevalence of COVID-19 among PLWH but equivocal data on increased mortality and worse clinical outco...

Descripción completa

Detalles Bibliográficos
Autores principales: Prabhu, Sandeep, Poongulali, Selvamuthu, Kumarasamy, Nagalingeswaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560116/
https://www.ncbi.nlm.nih.gov/pubmed/33083001
http://dx.doi.org/10.1016/j.jve.2020.100019
_version_ 1783595015009730560
author Prabhu, Sandeep
Poongulali, Selvamuthu
Kumarasamy, Nagalingeswaran
author_facet Prabhu, Sandeep
Poongulali, Selvamuthu
Kumarasamy, Nagalingeswaran
author_sort Prabhu, Sandeep
collection PubMed
description There is great concern about the impact of COVID-19 among the nearly 40 million people living with HIV (PLWH) worldwide. In this review, we surveyed current literature and found no evidence of higher prevalence of COVID-19 among PLWH but equivocal data on increased mortality and worse clinical outcomes. Having HIV does not confer protection against severe manifestations of COVID-19. Several studies looking at antiretroviral drugs against HIV to treat SARS-CoV-2 have shown no mortality benefit. Thus, there is no indication to change antiretroviral therapy (ART) regimens among virologically suppressed PLWH to prevent COVID-19. HIV care delivery has been adversely impacted in several countries during this pandemic but has created an opportunity for accelerating effective strategies like multi-month ART. Decentralizing HIV care in low-resource settings and incorporating telemedicine in high-resource settings will be critical in mitigating shocks to healthcare systems in the future.
format Online
Article
Text
id pubmed-7560116
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-75601162020-10-16 Impact of COVID-19 on people living with HIV: A review Prabhu, Sandeep Poongulali, Selvamuthu Kumarasamy, Nagalingeswaran J Virus Erad Review There is great concern about the impact of COVID-19 among the nearly 40 million people living with HIV (PLWH) worldwide. In this review, we surveyed current literature and found no evidence of higher prevalence of COVID-19 among PLWH but equivocal data on increased mortality and worse clinical outcomes. Having HIV does not confer protection against severe manifestations of COVID-19. Several studies looking at antiretroviral drugs against HIV to treat SARS-CoV-2 have shown no mortality benefit. Thus, there is no indication to change antiretroviral therapy (ART) regimens among virologically suppressed PLWH to prevent COVID-19. HIV care delivery has been adversely impacted in several countries during this pandemic but has created an opportunity for accelerating effective strategies like multi-month ART. Decentralizing HIV care in low-resource settings and incorporating telemedicine in high-resource settings will be critical in mitigating shocks to healthcare systems in the future. Elsevier 2020-10-15 /pmc/articles/PMC7560116/ /pubmed/33083001 http://dx.doi.org/10.1016/j.jve.2020.100019 Text en © 2020 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Prabhu, Sandeep
Poongulali, Selvamuthu
Kumarasamy, Nagalingeswaran
Impact of COVID-19 on people living with HIV: A review
title Impact of COVID-19 on people living with HIV: A review
title_full Impact of COVID-19 on people living with HIV: A review
title_fullStr Impact of COVID-19 on people living with HIV: A review
title_full_unstemmed Impact of COVID-19 on people living with HIV: A review
title_short Impact of COVID-19 on people living with HIV: A review
title_sort impact of covid-19 on people living with hiv: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560116/
https://www.ncbi.nlm.nih.gov/pubmed/33083001
http://dx.doi.org/10.1016/j.jve.2020.100019
work_keys_str_mv AT prabhusandeep impactofcovid19onpeoplelivingwithhivareview
AT poongulaliselvamuthu impactofcovid19onpeoplelivingwithhivareview
AT kumarasamynagalingeswaran impactofcovid19onpeoplelivingwithhivareview