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Generation of a cost-effective cell line for support of high-throughput isolation of primary human B cells and monoclonal neutralizing antibodies

The isolation of human monoclonal antibodies (mAbs) arising from natural infection with human pathogens has proven to be a powerful technology, facilitating the understanding of the host response to infection at a molecular level. mAbs can reveal sites of vulnerability on pathogens and illuminate th...

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Detalles Bibliográficos
Autores principales: Whaley, Rachael E., Ameny, Sarah, Arkatkar, Tanvi, Seese, Aaron, Wall, Abigail, Khan, Iram, Carter, Joseph J., Scherer, Erin M., Rawlings, David J., Galloway, Denise A., McElrath, M. Juliana, Cohen, Kristen W., McGuire, Andrew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560121/
https://www.ncbi.nlm.nih.gov/pubmed/33069767
http://dx.doi.org/10.1016/j.jim.2020.112901

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