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Anti-Tubercular Properties of 4-Amino-5-(4-Fluoro-3- Phenoxyphenyl)-4H-1,2,4-Triazole-3-Thiol and Its Schiff Bases: Computational Input and Molecular Dynamics

In the present investigation, the parent compound 4-amino-5-(4-fluoro-3-phenoxyphenyl)-4H-1,2,4-triazole-3-thiol (1) and its Schiff bases 2, 3, and 4 were subjected to whole-cell anti-TB against H37Rv and multi-drug-resistant (MDR) strains of Mycobacterium tuberculosis (MTB) by resazurin microtiter...

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Detalles Bibliográficos
Autores principales:	Venugopala, Katharigatta N., Kandeel, Mahmoud, Pillay, Melendhran, Deb, Pran Kishore, Abdallah, Hassan H., Mahomoodally, Mohamad Fawzi, Chopra, Deepak
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560126/ https://www.ncbi.nlm.nih.gov/pubmed/32878018 http://dx.doi.org/10.3390/antibiotics9090559

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