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Poly(9H-carbazole) as a Organic Semiconductor for Enzymatic and Non-Enzymatic Glucose Sensors

Organic semiconductors and conducting polymers are the most promising next-generation conducting materials for electrochemical biosensors as the greener and cheaper alternative for electrodes based on transition metals or their oxides. Therefore, polycarbazole as the organic semiconducting polymer w...

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Detalles Bibliográficos
Autores principales: Bagdžiūnas, Gintautas, Palinauskas, Delianas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560144/
https://www.ncbi.nlm.nih.gov/pubmed/32842552
http://dx.doi.org/10.3390/bios10090104
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author Bagdžiūnas, Gintautas
Palinauskas, Delianas
author_facet Bagdžiūnas, Gintautas
Palinauskas, Delianas
author_sort Bagdžiūnas, Gintautas
collection PubMed
description Organic semiconductors and conducting polymers are the most promising next-generation conducting materials for electrochemical biosensors as the greener and cheaper alternative for electrodes based on transition metals or their oxides. Therefore, polycarbazole as the organic semiconducting polymer was electrochemically synthesized and deposited on working electrode. Structure and semiconducting properties of polycarbazole have theoretically and experimentally been analyzed and proved. For these electrochemical systems, a maximal sensitivity of 14 μA·cm(−2)·mM(−1), a wide linear range of detection up to 5 mM, and a minimal limit of detection of around 0.2 mM were achieved. Moreover, Michaelis’s constant of these sensors depends not only on the enzyme but on the material of electrode and applied potential. The electrocatalytic mechanism and performance of the non- and enzymatic sensors based on this material as a conducting layer have been discussed by estimating pseudocapacitive and faradaic currents and by adding glucose as an analyte at the different applied potentials. In this work, the attention was focused on the electrochemical origin and mechanism involved in the non- and enzymatic oxidation and reduction of glucose.
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spelling pubmed-75601442020-10-22 Poly(9H-carbazole) as a Organic Semiconductor for Enzymatic and Non-Enzymatic Glucose Sensors Bagdžiūnas, Gintautas Palinauskas, Delianas Biosensors (Basel) Article Organic semiconductors and conducting polymers are the most promising next-generation conducting materials for electrochemical biosensors as the greener and cheaper alternative for electrodes based on transition metals or their oxides. Therefore, polycarbazole as the organic semiconducting polymer was electrochemically synthesized and deposited on working electrode. Structure and semiconducting properties of polycarbazole have theoretically and experimentally been analyzed and proved. For these electrochemical systems, a maximal sensitivity of 14 μA·cm(−2)·mM(−1), a wide linear range of detection up to 5 mM, and a minimal limit of detection of around 0.2 mM were achieved. Moreover, Michaelis’s constant of these sensors depends not only on the enzyme but on the material of electrode and applied potential. The electrocatalytic mechanism and performance of the non- and enzymatic sensors based on this material as a conducting layer have been discussed by estimating pseudocapacitive and faradaic currents and by adding glucose as an analyte at the different applied potentials. In this work, the attention was focused on the electrochemical origin and mechanism involved in the non- and enzymatic oxidation and reduction of glucose. MDPI 2020-08-23 /pmc/articles/PMC7560144/ /pubmed/32842552 http://dx.doi.org/10.3390/bios10090104 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bagdžiūnas, Gintautas
Palinauskas, Delianas
Poly(9H-carbazole) as a Organic Semiconductor for Enzymatic and Non-Enzymatic Glucose Sensors
title Poly(9H-carbazole) as a Organic Semiconductor for Enzymatic and Non-Enzymatic Glucose Sensors
title_full Poly(9H-carbazole) as a Organic Semiconductor for Enzymatic and Non-Enzymatic Glucose Sensors
title_fullStr Poly(9H-carbazole) as a Organic Semiconductor for Enzymatic and Non-Enzymatic Glucose Sensors
title_full_unstemmed Poly(9H-carbazole) as a Organic Semiconductor for Enzymatic and Non-Enzymatic Glucose Sensors
title_short Poly(9H-carbazole) as a Organic Semiconductor for Enzymatic and Non-Enzymatic Glucose Sensors
title_sort poly(9h-carbazole) as a organic semiconductor for enzymatic and non-enzymatic glucose sensors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560144/
https://www.ncbi.nlm.nih.gov/pubmed/32842552
http://dx.doi.org/10.3390/bios10090104
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